2357105-36-1

(S)-Thalidomide-4-OH Chemical Structure
2357105-36-1

Chemical Structure

(S)-Thalidomide-4-OH

  • CAS No.: 2357105-36-1
  • Formula:C13H10N2O5
  • Molecular Weight:274.23

IUPAC Name: (S)-2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

InChIKey: XMPJICVFSDYOEG-ZETCQYMHSA-N

SMILES: OC1=C2C(N(C(C2=CC=C1)=O)[C@H]3CCC(NC3=O)=O)=O

Biological Activity: (S)-Thalidomide-4-OH is the S-isomer of Thalidomide-4-OH (HY-103596). Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs[1].

Cat. No. Product Name Purity Description Pricing
HY-W674436
(S)-Thalidomide-4-OH 98.0% (S)-Thalidomide-4-OH is the S-isomer of Thalidomide-4-OH (HY-103596). Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
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