Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
217 Results for "
Thymidine
" in MedChemExpress (MCE) Product Catalog:
Products (217)
217 Results for "Thymidine" in MCE Product Catalog:
27
82
82 Publications Verification
Synonyms: BrdU; 5-Bromo-2'-deoxyuridine; BUdR
Áreas de investigación:
5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.
37
Target:
Áreas de investigación:
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
30
30 Cited Publications
Referencia número: HY-B0016
No. CAS: 154361-50-9
Áreas de investigación:
Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase.
23
23 Cited Publications
Referencia número: HY-17422
No. CAS: 59277-89-3
Synonyms: Aciclovir; Acycloguanosine
Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia .
23
23 Cited Publications
Referencia número: HY-17422A
No. CAS: 69657-51-8
Synonyms: Aciclovir sodium; Acycloguanosine sodium
Acyclovir (Aciclovir) sodium is a potent, orally active antiviral agent. Acyclovir sodium has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir sodium induces cell cycle perturbation and apoptosis. Acyclovir sodium prevents bacterial infections during induction therapy for acute leukaemia .
12
12 Cited Publications
Synonyms: 5-Iodo-2′-deoxyuridine; 5-IUdR; IdUrd
Idoxuridine (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC50 value of 4.3 μM . Idoxuridine shows anti-orthopoxvirus activity.
5
5 Cited Publications
Referencia número: HY-A0063
No. CAS: 183204-72-0
Target:
Áreas de investigación:
Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research.
5
5 Cited Publications
Referencia número: HY-A0063A
No. CAS: 183204-74-2
Áreas de investigación:
Tipiracil is a thymidine phosphorylase (TPase) inhibitor.
4
Áreas de investigación:
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. The composition of Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). Trifluridine/tipiracil hydrochloride mixture (TAS-102) shows the antitumor activity mainly via the inhibition of thymidylate synthase (TS) and incorporation into DNA .
2
2 Cited Publications
Synonyms: Bromovinyldeoxyuridine; BVDU
Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.
2
2 Cited Publications
Synonyms: Ro 21-9738; 5-Fluoro-5'-deoxyuridine; 5'-DFUR
Target:
Áreas de investigación:
Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .
2
2 Cited Publications
Referencia número: HY-148980A
No. CAS: 33378-44-8
Target:
Áreas de investigación:
Polyinosinic acid sodium is the sodium form of Polyinosinic acid (HY-148980). Polyinosinic acid is a single stranded homonucleic acid, which is a Toll-like Receptor 3 (TLR3) ligand. Polyinosinic acid enhances cellular immune response through TLR3 and TRIF. Polyinosinic acid has potential applications in immune regulation .
1
1
1 Cited Publications
Synonyms: TMP disodium salt
1
1 Cited Publications
Referencia número: HY-W113081
No. CAS: 6741-73-7
Synonyms: 1-(4-Thio-beta-D-ribofuranosyl)uracil
Target:
Áreas de investigación:
4′-Thiouridine (1-(4-Thio-beta-D-ribofuranosyl)uracil) is a thio analog of thymidine. 4′-Thiouridine can be used to synthesize 4'-thionucleosides with antiviral and anticancer activities. 4′-Thiouridine can be used for RNA-sequencing .
Referencia número: HY-20140
No. CAS: 40615-39-2
Synonyms: 5'-O-(4,4'-Dimethoxytrityl)Thymidine
Áreas de investigación:
5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides .
Referencia número: HY-B1011
No. CAS: 15176-29-1
Synonyms: EUDR
Target:
Áreas de investigación:
Edoxudine is an antiviral active molecule and thymidine analog. Edoxudine is effective against herpes simplex virus .
Synonyms: dTDP sodium
Target:
Target:
Áreas de investigación:
Thymidine 5′-monophosphate p-nitrophenyl ester sodium (Compound 2a) is the derivative of thymidine 5'-phosphate (TMP). Thymidine 5′-monophosphate p-nitrophenyl ester sodium is potential as an antitumor prodrug .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
