1. Anti-infection
  2. HSV
  3. Idoxuridine

Idoxuridine (Synonyms: 5-Iodo-2′-deoxyuridine; IdUrd; 5-IUdR)

Cat. No.: HY-B0307 Purity: 99.88%
Handling Instructions

Idoxuridine is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM.

For research use only. We do not sell to patients.

Idoxuridine Chemical Structure

Idoxuridine Chemical Structure

CAS No. : 54-42-2

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
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1 g USD 72 In-stock
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5 g USD 216 In-stock
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10 g USD 360 In-stock
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Description

Idoxuridine is an antiviral agent for feline herpesvirus type-1 with IC50 of 4.3 μM. Target: herpesvirus type-1 Idoxuridine is mainly used topically to treat herpes simplex keratitis. Epithelial lesions, especially initial attacks presenting with a dendritic ulcer, are most responsive to therapy, while infection with stromal involvement are less responsive. Idoxuridine is ineffective against herpes simplex virus type 2 and varicella-zoster.

Clinical Trial
Molecular Weight

354.10

Formula

C₉H₁₁IN₂O₅

CAS No.

54-42-2

SMILES

OC[[email protected]@H]1[[email protected]](C[[email protected]](N2C(NC(C(I)=C2)=O)=O)O1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 65 mg/mL (183.56 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8241 mL 14.1203 mL 28.2406 mL
5 mM 0.5648 mL 2.8241 mL 5.6481 mL
10 mM 0.2824 mL 1.4120 mL 2.8241 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.06 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.88%

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Keywords:

Idoxuridine5-Iodo-2′-deoxyuridineIdUrd5-IUdRHSVHerpes simplex virusInhibitorinhibitorinhibit

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Idoxuridine
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