13 Results for "

Yes-associated protein

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Yes-associated protein" in MCE Product Catalog:

  • Targets Recommended:
11
11 Publications Verification
Cat. No.: HY-13285
CAS No.: 355025-24-0
Purity:  98.88%
Synonyms: Debio 0719
Target:  

LPL Receptor YAP

Research Areas:  

Neurological Disease Cancer

Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK . Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-Y0669
CAS No.: 535-75-1
Pipecolic acid is an orally bioavailable, blood-brain barrier-permeable metabolite of lysine with antioxidant, inhibitor, and inducer activity. Pipecolic acid modulates the YAP-GPX4 signaling pathway, reduces retinal vascular tube formation, and mitigates ferroptosis. Pipecolic acid potentiates voltage-sensitive Ca 2+ channel currents and induces neuronal apoptosis. Pipecolic acid can be used for the research of diabetic retinopathy .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-125016
CAS No.: 2230640-94-3
Purity:  99.78%
Synonyms: TAZ-K
Target:  

YAP

Research Areas:  

Cardiovascular Disease Cancer

TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P86386
Synonyms: YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P80374
Synonyms: YAP65, YAP1, Transcriptional coactivator YAP1, Yes-associated protein 1, protein yorkie homolog, Yes-associated protein YAP65 homolog

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, IP, FC

Reactivity:  

Human

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P80481
Synonyms: YAP65, YAP1, Transcriptional coactivator YAP1, Yes-associated protein 1, protein yorkie homolog, Yes-associated protein YAP65 homolog

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse

loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P80864
Synonyms: YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-N0754
CAS No.: 877822-40-7
Eupalinolide A is a Yes-associated protein (YAP) degrader and HSP70 inducer. Eupalinolide A inhibits osteogenic differentiation of tendon-derived stem cells (TDSCs). Eupalinolide A induces autophagy in hepatocellular carcinoma cells via activating the ROS/ERK signaling pathway. Eupalinolide A protects PAM212 cells from UVB-, Menadione (HY-B0332)-, or heat shock-induced apoptosis. Eupalinolide A alleviates trauma-induced heterotopic ossification (HO) of Achilles tendon and inhibits growth of MHCC97-L and HCCLM3 hepatocellular carcinoma xenograft tumors in mice. Eupalinolide A can be used for the study of traumatic heterotopic ossification of tendons and hepatocellular carcinoma .
loading...
    loading...
Cat. No.: HY-157083
Target:  

YAP

Research Areas:  

Cancer

mCMY020 is a covalent inhibitor of TEAD. mCMY020 effectively reduces YAP (Yes-associated protein)-driven transcription and selectively slows the proliferation of Hippo-deficient cancer cells. mCMY020 can be used in cancer research .
loading...
    loading...
Cat. No.: HY-13285R
CAS No.: 355025-24-0
Synonyms: Debio 0719 (Standard)
Ki16425 (Standard) is the analytical standard of Ki16425. This product is intended for research and analytical applications. Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK . Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells .
loading...
    loading...
Cat. No.: HY-P704253
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: YAP1; YAP65; Transcriptional coactivator YAP1; Yes-associated protein 1; protein yorkie homolog; Yes-associated protein YAP65 homolog
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P86167
Synonyms: YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Host:  

Rabbit

Application:  

WB, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
Cat. No.: HY-P80864A
Synonyms: YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
  • 1