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Results for "

acyl donor

" in MedChemExpress (MCE) Product Catalog:

16

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Biochemical Assay Reagents

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Peptides

2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-141466
    Crotonyl-CoA

    		Endogenous Metabolite Histone Acetyltransferase Infection Metabolic Disease Inflammation/Immunology
    Crotonyl-CoA, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA can be used for the research of LPS-induced inflammatory response .
    Crotonyl-CoA
  • HY-141466A
    Crotonyl-CoA tetrasodium

    		Endogenous Metabolite Histone Acetyltransferase Infection Metabolic Disease Inflammation/Immunology
    Crotonyl-CoA tetrasodium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetrasodium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetrasodium acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetrasodium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetrasodium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetrasodium can be used for the research of LPS-induced inflammatory response .
    Crotonyl-CoA tetrasodium
  • HY-CE02017
    trans-Feruloyl-CoA

    trans-Feruloyl-coenzyme A

    		 Biochemical Assay Reagents Metabolic Disease
    trans-Feruloyl-CoA (trans-Feruloyl-coenzyme A) is a derivative of coenzyme A. trans-Feruloyl-CoA also acts as an activated acyl donor involved in the synthesis of cell wall components such as lignin and feruloylated polysaccharides .
    trans-Feruloyl-CoA
  • HY-116284
    Methyl β-D-glucopyranoside

    Methyl β-D-glucoside

    		 Drug Intermediate Others
    Methyl β-D-glucopyranoside (Methyl β-D-glucoside) is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can generate biologically active derivatives (such as 6-O-caffeoyl glucoside). Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside) .
    Methyl β-D-glucopyranoside
  • HY-W012802
    Methyl 1H-pyrrole-2-carboxylate

    		Drug Intermediate Others
    Methyl 1H-pyrrole-2-carboxylate is a drug intermediate that can act as an acyl donor. Methyl 1H-pyrrole-2-carboxylate can be synthesized into a series of pyrrolidine derivatives through tranesterification reactions with various alcohols .
    Methyl 1H-pyrrole-2-carboxylate
  • HY-162470
    DBPR728

    		Aurora Kinase Cancer
    DBPR728 is an acyl prodrug of 6K465 that carries fewer hydrogen bond donors. 6K465 acts as an Aurora kinase inhibitor that destabilizes MYC family cancer proteins and has antitumor efficacy. DBPR728 has the potential to inhibit cancers that overexpress C-MYC and N-MYC, with a 10-fold increase in oral bioavailability compared to 6K465 .
    DBPR728
  • HY-P4866
    Q-Peptide

    		Integrin Transglutaminase Akt p38 MAPK ERK Caspase Apoptosis Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Q-Peptide is an angiopoietin-1 derived peptide (QHREDGS). Q-Peptide interacts with β1-integrin, binds to integrins on the surface of osteoblasts, and serves as an acyl donor substrate for Streptomyces mobaraensis transglutaminase. Q-Peptide activates Akt, MAPKp42/44, ILK, ERK1/2, and downregulates caspase-3/7. Q-Peptide inhibits cell apoptosis, enhances cell adhesion and migration, and promotes osteoblast differentiation, bone matrix deposition and mineralization. Q-Peptide can be used in studies related to myocardial infarction, bone regeneration, diabetic wound repair and human induced pluripotent stem cells .
    Q-Peptide
  • HY-166309
    Crotonyl-CoA tetralithium

    		Endogenous Metabolite Histone Acetyltransferase Infection Metabolic Disease Inflammation/Immunology
    Crotonyl-CoA tetralithium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetralithium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetralithium acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetralithium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetralithium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetralithium can be used for the research of LPS-induced inflammatory response .
    Crotonyl-CoA tetralithium
  • HY-148869A
    Hexanoyl-coenzyme A triammonium

    06:0 Coenzyme A triammonium

    		 Biochemical Assay Reagents Metabolic Disease
    Hexanoyl-Coenzyme A triammonium (06:0 Coenzyme A) is a medium-chain fatty acyl CoA that is an acyl donor substrate for ghrelin O-acyltransferase (GOAT) .
    Hexanoyl-coenzyme A triammonium
  • HY-N8821
    1-(4-Hydroxybenzoyl)glucose

    		Others Metabolic Disease
    1-(4-Hydroxybenzoyl)glucose, a natural product found in Moricandia arvensis, Rhodiola chrysanthemifolia, acts as a bifunctional acyl and glucosyl donor .
    1-(4-Hydroxybenzoyl)glucose
  • HY-126866
    Lankacidin C 8-acetate

    		Bacterial Infection
    Lankacidin C 8-acetate is an antibiotic with antibacterial activity. Lankacidin C 8-acetate, as a component of the Lankacidin group (T-2636) antibiotics, shows inhibitory effects against specific bacteria. Lankacidin C 8-acetate can generate other esterates by reacting with different acyl donors, indicating its importance in the synthesis of antibiotics .
    Lankacidin C 8-acetate
  • HY-E71009
    N-Acylmannosamine 1-Dehydrogenase, Pseudomonas sp.

    		Biochemical Assay Reagents Metabolic Disease
    N-Acylmannosamine 1-Dehydrogenase, Pseudomonas sp. (EC 1.1.1.233) acts on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The two substrates of this enzyme are N-acyl-D-mannosamine and NAD+, whereas its 3 products are N-acyl-D-mannosaminolactone, NADH, and H+.
    N-Acylmannosamine 1-Dehydrogenase, Pseudomonas sp.
  • HY-E70009A
    Acyl-CoA oxidase, Arthrobacter sp.

    		Biochemical Assay Reagents Metabolic Disease
    Acyl-CoA oxidase, Arthrobacter sp. (EC 1.3.3.6) is a redox enzyme that acts on the CH-CH group in donor molecules and uses oxygen as an acceptor. Acyl-CoA oxidase, Arthrobacter sp. (EC 1.3.3.6) is involved in three metabolic pathways: fatty acid metabolism, polyunsaturated fatty acid biosynthesis, and the PPAR signaling pathway.
    Acyl-CoA oxidase, Arthrobacter sp.
  • HY-E71190
    13-Hydroxylupanine O-tigloyltransferase

    		Biochemical Assay Reagents Others
    13-Hydroxylupanine O-tigloyltransferase (EC 2.3.1.93) can act as an acyl donor. 13-Hydroxylupanine O-tigloyltransferase (EC 2.3.1.93) is involved in the synthesis of lupanine alkaloids.
    13-Hydroxylupanine O-tigloyltransferase
  • HY-116284A
    Methyl β-D-glucopyranoside hemihydrate

    Methyl β-D-glucoside hemihydrate

    		 Drug Intermediate Others
    Methyl β-D-glucopyranoside (Methyl β-D-glucoside) hemihydrate is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside hemihydrate participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside hemihydrate can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside) .
    Methyl β-D-glucopyranoside hemihydrate
  • HY-116284R
    Methyl β-D-glucopyranoside (Standard)

    Methyl β-D-glucoside (Standard)

    		 Reference Standards Drug Intermediate Others
    Methyl β-D-glucopyranoside (Methyl β-D-glucoside) (Standard) is the analytical standard of Methyl β-D-glucopyranoside. This product is intended for research and analytical applications. Methyl β-D-glucopyranoside is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside).
    Methyl β-D-glucopyranoside (Standard)

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