2 Results for "

all-hydrocarbon peptide stapling

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "all-hydrocarbon peptide stapling" in MCE Product Catalog:

Fmoc-(S)-2-(4-pentenyl)Ala-OH
Fmoc-(S)-2-(4-pentenyl)Ala-OH
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Cat. No.: HY-W004864
CAS No.: 288617-73-2
Target:  

Amino Acid Derivatives

Research Areas:  

Others

Fmoc-(S)-2-(4-pentenyl) Ala-OH is an Fmoc-protected unnatural amino acid. Fmoc-(S)-2-(4-pentenyl) Ala-OH can be used for polypeptide synthesis, such as NYAD-13 (HY-P10834) .
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Fmoc-(R)-2-(7-octenyl)Ala-OH
Fmoc-(R)-2-(7-octenyl)Ala-OH
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Cat. No.: HY-W006886
CAS No.: 945212-26-0
Target:  

Amino Acid Derivatives

Research Areas:  

Others

Fmoc-(R)-2-(7-octenyl) Ala-OH is an unnatural Fmoc-protected amino acid and modification module. Fmoc-(R)-2-(7-octenyl) Ala-OH serves as a key building block for all-hydrocarbon cross-linking modification of antimicrobial peptides, and facilitates the generation of stapled peptide derivatives. When introduced into specific sites of the parent peptide, Fmoc-(R)-2-(7-octenyl) Ala-OH effectively increases the α-helix content of the peptide chain, thereby significantly enhancing its antimicrobial activity and proteolytic stability. Fmoc-(R)-2-(7-octenyl) Ala-OH is widely used in research on bacterial infections and the development of related antimicrobial agents . Stapled peptide is a specially chemically modified polypeptide. It locks the peptide chain into a stable α-helical structure by introducing a "staple"-like chemical bridge (usually an all-carbon backbone) at specific positions of the peptide chain.
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