4 Results for "

anti-MetS

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "anti-MetS" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-151923
CAS No.: 3038756-30-5
Purity:  99.50%
Research Areas:  

Metabolic Disease

ATF3 inducer 1 is a potent ATF3 inducer. ATF3 inducer 1 increases the ATF3 protein and ATF3 mRNA expression. ATF3 inducer 1 shows anti-MetS activity in mouse .
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Cat. No.: HY-P990073
CAS No.: 2648058-48-2
Synonyms: REGN-5093

Target:  

c-Met/HGFR

Research Areas:  

Cancer

Davutamig (REGN-5093) is a human IgG4-kappa, anti-MET bispecific antibody. Davutamig binds 2 distinct epitopes of MET, blocking ligand binding and inducing MET internalization and degradation. Davutamig is applicable to the research of advanced non-small cell lung cancer with MET gene abnormalities .
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Cat. No.: HY-P991660

Target:  

c-Met/HGFR

Research Areas:  

Cancer

ARGX-111 is an anti-MET antibody. ARGX-111 blocks HGF-dependent and -independent signaling, downregulating MET expression on the tumor cell surface. ARGX-111 depletes MET-expressing circulating tumor cells through enhanced antibody-dependent cell-mediated cytotoxicity (ADCC), thereby inhibiting tumor metastasis. ARGX-111 depletes circulating tumor cells and inhibits bone and lung metastasis in an orthotopic mouse model of metastatic breast cancer. ARGX-111 is promising for research in breast cancer and other cancers .
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Cat. No.: HY-171191
REGN5093-M114 is a bispecific antibody-drug conjugate (ADC) that targets two epitopes of the MET receptor tyrosine kinase inhibits the proliferation of NSCLC cells, exhibits antitumor efficacy in mouse models. REGN5093-M114 is composed of the human monoclonal anti-MET antibody Davutamig (HY-P990073) and the tubulin-inhibiting linker-payload (HY-148528) .
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