8 Results for "

arylnaphthalene

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "arylnaphthalene" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P0171
CAS No.: 664334-36-5
Synonyms: BKT140 (4-fluorobenzoyl); BL-8040; TF14016
Target:  

CXCR

Research Areas:  

Endocrinology Cancer

Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ~1 nM.
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3
3 Cited Publications
Cat. No.: HY-N2532
CAS No.: 22055-22-7
Diphyllin is an orally active V-ATPase inhibitor (IC50=17 nM) and HIV-1 inhibitor (IC50=0.38 μM). Diphyllin blocks the acidification of osteoclast lysosomes and bone resorption lacunas (IC50=0.6 nM for acid influx inhibition), thereby inhibiting bone resorption. Diphyllin can effectively inhibit osteoclast-mediated bone resorption and has no effect on osteoblastic bone formation. Diphyllin can be used in the research of bone metabolism-related diseases and has the potential to inhibit diseases related to excessive bone resorption .
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2
2 Cited Publications
Cat. No.: HY-P0009A
CAS No.: 145672-81-7
Synonyms: SB-75 acetate
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology

Cetrorelix (SB-75) acetate is a competitive gonadotropin-releasing hormone receptor (GnRHR) antagonist with a Kd of 0.19 nM. Cetrorelix acetate inhibits the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby suppressing the secretion of downstream sex steroids. Cetrorelix acetate prevents ovulation, induces reversible reproductive shutdown and azoospermia, reduces ovarian fibrosis, improves superovulation outcomes, and inhibits chemotherapy-induced mitochondria-dependent apoptosis. Cetrorelix acetate is applicable for fertility assistance research .
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1
1 Cited Publications
Cat. No.: HY-P4452
CAS No.: 209006-18-8
Research Areas:  

Endocrinology

PRL 2915 is a potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM .
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Cat. No.: HY-N9351
CAS No.: 30021-77-3
Synonyms: Diphyllin O-glucoside
Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 µM. Cleistanthin B also exhibits antitumor, diuretic and antihypertensive effects in vivo .
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Cat. No.: HY-N2247
CAS No.: 36531-08-5
Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .
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Cat. No.: HY-P0009B
CAS No.: 130143-01-0
Synonyms: SB-75 diacetate
Target:  

GnRH Receptor

Research Areas:  

Neurological Disease Endocrinology

Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM .
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Cat. No.: HY-131374
CAS No.: 368874-31-1
Target:  

CXCR

Research Areas:  

Cancer

TN14003 is a CXCR4 inhibitor. TN14003 has antitumor activity .
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