64 Results for "

beta glucan

" in MedChemExpress (MCE) Product Catalog:
Products (64)

64 Results for "beta glucan" in MCE Product Catalog:

21
21 Publications Verification
Cat. No.: HY-16321
CAS No.: 208538-73-2
Synonyms: FK 463 sodium
Target:  

Fungal Antibiotic

Research Areas:  

Infection Cancer

Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.
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21
21 Publications Verification
Cat. No.: HY-17579
CAS No.: 235114-32-6
Synonyms: FK463
Target:  

Fungal Antibiotic

Research Areas:  

Infection Cancer

Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.
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11
11 Cited Publications
Cat. No.: HY-17006
CAS No.: 179463-17-3
Synonyms: MK-0991 diacetate; L-743872 diacetate
Research Areas:  

Infection Cancer

Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
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11
11 Cited Publications
Cat. No.: HY-17006A
CAS No.: 162808-62-0
Synonyms: MK-0991; L-743872
Research Areas:  

Infection Cancer

Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
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2
2 Cited Publications
Cat. No.: HY-W145521
CAS No.: 9051-97-2
Synonyms: β glucan
β-1,3-Glucan (β Glucan) is an orally active polysaccharide composed of glucose polymers. β-1,3-Glucan increase the activity of IKKβ kinase, enhances the production of nitric oxide. β-1,3-Glucan improves resistance to Vibrio harveyi infection. β-1,3-Glucan enhances immune response, promotes blood pressure recovery, reduces lung, kidney and liver damage, inhibits the growth of syngeneic tumors .
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2
2 Cited Publications
Cat. No.: HY-119109
CAS No.: 9008-22-4
Purity:  ≥98.0%
Laminaran is an β-1-3-glucan and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .
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1
1 Cited Publications
Cat. No.: HY-139413
CAS No.: 9041-22-9
Purity:  99.00%
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .
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1
1 Cited Publications
Cat. No.: HY-107126
CAS No.: 1207753-03-4
Purity:  99.83%
Synonyms: MK 3118; SCY-078
Target:  

Fungal

Research Areas:  

Infection

Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections .
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1
1 Cited Publications
Cat. No.: HY-107126A
CAS No.: 1965291-08-0
Purity:  99.38%
Synonyms: MK 3118 citrate; SCY-078 citrate
Target:  

Fungal

Research Areas:  

Infection

Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections .
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1
1 Cited Publications
Cat. No.: HY-N6924
CAS No.: 80930-74-1
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .
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1
1 Cited Publications
Cat. No.: HY-134655
CAS No.: 384376-42-5
Purity:  99.14%
Target:  

Fungal

Research Areas:  

Infection Inflammation/Immunology

D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity .
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Cat. No.: HY-E70013
CAS No.: 37288-51-0
Synonyms: endo-1,3:1,4-β-D-glucanase
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .
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Cat. No.: HY-P3004
CAS No.: 9025-37-0
Synonyms: Lyticase
Research Areas:  

Infection

Endo-1,3-β-glucanase (Lyticase) is an endoenzyme that can specifically cleave β-1,3-glycosidic bonds. Endo-1,3-β-glucanase recognizes and binds to β-1,3-glucan chains, catalyzing the cleavage of glycosidic bonds and hydrolyzing polysaccharides into oligosaccharides. Endo-1,3-β-glucanase eliminates vaginal Candida. Endo-1,3-β-glucanase can be used in the study of recurrent Candida vaginitis .
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Cat. No.: HY-W050145
CAS No.: 498-07-7
Synonyms: 1,6-Anhydro-β-D-glucopyranose; 1,6-Anhydro-β-D-glucose
Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .
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Cat. No.: HY-147295
CAS No.: 53238-80-5
Synonyms: BTH 1677; Imprime PGG
Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response .
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Cat. No.: HY-165126
CAS No.: 9050-67-3
Synonyms: SPG
Schizophyllan (SPG) is an orally active extracellular β-glucan produced by the fungus Schizophyllum commune. Schizophyllan improves mitochondrial function and protects against metabolic liver injury by activating the SIRT3 pathway. Schizophyllan inhibits osteoclastogenesis and promotes osteoblast differentiation by suppressing the phosphorylation of JNK/p38, as well as downregulating PGC1β/PPARγ, c-Fos and NFATc1. Recognized via Dectin-1, schizophyllan enables precise delivery of oligonucleotide drugs and antigens to antigen-presenting cells, thus holding great potential in the treatment of inflammatory diseases and vaccine development .
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Cat. No.: HY-W050145S
CAS No.: 2483832-05-7
Synonyms: 1,6-Anhydro-β-D-glucopyranose-d7; 1,6-Anhydro-β-D-glucose-d7
Levoglucosan-d7 is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .
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Cat. No.: HY-N8537
CAS No.: 260979-95-1
Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .
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Cat. No.: HY-N15135
CAS No.: 9040-27-1
Arabinoxylan Medium viscosity is an orally active Dectin-1 splice variant modulator, glucose absorption inhibitor, and chyme viscosity enhancer. Arabinoxylan Medium viscosity inhibits particulate β-glucan-induced Dectin-1A activation and mildly suppresses Dectin-1B activation. In human dendritic cells stimulated with particulate β-glucan, Arabinoxylan Medium viscosity reduces the production of IL-10 and TNF-α, and increases the production of IL-4 and IL-23. Arabinoxylan Medium viscosity also supports antifungal immune responses without activating TLR2, TLR4 or TLR5, and does not induce cytokine production when used to stimulate human dendritic cells alone. Arabinoxylan Medium viscosity increases small intestinal chyme viscosity, gets degraded in the large intestine to produce short-chain fatty acids, reduces glucose absorption and insulin response, and improves glucose homeostasis. Arabinoxylan Medium viscosity supports microbial fermentation and the growth of beneficial microbiota in the gastrointestinal tract, prevents bile acid reabsorption, and delays starch digestion. Arabinoxylan Medium viscosity can be used in research related to type 2 diabetes, impaired glucose tolerance, and metabolic syndrome .
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Cat. No.: HY-163462
CAS No.: 160097-32-5
Target:  

Fungal

Research Areas:  

Infection

Poacic Acid is a plant-derived stilbenoid with an antifungal activity. Poacic Acid localizes to the yeast cell wall and disrupts the production and assembly of β-1,3-glucan in the fungal cell walls. Poacic Acid exhibits fungicidal activity to Saccharomyces cerevisiae and plasma membrane-compromised Candida albicans mutants .
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