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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
c-ros oncogene 1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "c-ros oncogene 1" in MCE Product Catalog:
Cat. No.: HY-159147
CAS No.: 2570251-69-1
Target:
Research Areas:
SIAIS039 is an orally active c-ros oncogene 1 (ROS1)-specific PROTAC with DC50s of 154.46 nM, 126.47 nM, 143.69 nM for HCC78 cells, Ba/F3 expressing the CD74-ROS1 fusion and Ba/F3 expressing the SDC4-ROS1 fusion, respectively. SIAIS039 suppresses cell proliferation, induces cell cycle arrest and apoptosis, and inhibits clonogenicity against ROS1-positive cells. SIAIS039 demonstrates anti-tumour effects against ROS1-driven tumor growth vivo. SIAIS039 is composed of the ALK inhibitor Brigatinib (HY-12857), a linker EM-12 (HY-138793), and a VHL ligand E3 ubiquitin ligase 1-Butyne (Red: Brigatinib; Blue: VHL ligand; Black: linker) .
Cat. No.: HY-P706095
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ros1; Proto-oncogene C-ros-1; ros Proto-oncogene 1, Receptor Tyrosine Kinase; V-ros UR2 Sarcoma Virus oncogene Homolog 1 (Avian); MCF3; ros Proto-oncogene 1 , Receptor Tyrosine Kinase; ros; Transmembrane Tyrosine-Specific Protein Kinase; C-ros-1; Receptor Tyrosine Kinase C-ros oncogene 1; V-ros Avian UR2 Sarcoma Virus oncogene Homolog 1; Tyrosine-Protein Kinase Receptor; C-ros oncogene 1 , Receptor Tyrosine Kinase; C-ros Receptor Tyrosine Kinase; Proto-oncogene Tyrosine-Protein Kinase ros; Proto-oncogene C-ros
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706096
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ros1; Proto-oncogene C-ros-1; ros Proto-oncogene 1, Receptor Tyrosine Kinase; V-ros UR2 Sarcoma Virus oncogene Homolog 1 (Avian); MCF3; ros Proto-oncogene 1 , Receptor Tyrosine Kinase; ros; Transmembrane Tyrosine-Specific Protein Kinase; C-ros-1; Receptor Tyrosine Kinase C-ros oncogene 1; V-ros Avian UR2 Sarcoma Virus oncogene Homolog 1; Tyrosine-Protein Kinase Receptor; C-ros oncogene 1 , Receptor Tyrosine Kinase; C-ros Receptor Tyrosine Kinase; Proto-oncogene Tyrosine-Protein Kinase ros; Proto-oncogene C-ros
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-120387
CAS No.: 1253286-90-6
Research Areas:
SMU-B is the orally active inhibitor for ALK (IC50<0.5 nM), c-ros oncogene 1 (ROS1), c-MET (IC50=1.87 nM) and AXL (IC50=28.9 nM). SMU-B inhibits the proliferation of MKN45, H1993 and H441 with IC50s of 0.02 μM, 1.58 μM and 2.82 μM, respectively. SMU-B exhibits antitumor efficacy in mouse models .
Cat. No.: HY-P87054
Synonyms: c ros 1 antibody; c ros antibody; c ros oncogene 1 receptor tyrosine kinase antibody; c ros receptor tyrosine kinase antibody; c ros1 antibody; MCF 3 antibody; MCF3 antibody; oncogene ros antibody; OTTHUMP00000017814 antibody; OTTHUMP00000017815 antibody; c ros 1 antibody; c ros antibody; c ros oncogene 1 receptor tyrosine kinase antibody; c ros receptor tyrosine kinase antibody; c ros1 antibody; MCF 3 antibody; MCF3 antibody; oncogene ros antibody; OTTHUMP00000017814 antibody; OTTHUMP00000017815 antibody; OTTHUMP00000040389 antibody; Proto oncogene c ros 1 protein antibody; Proto oncogene c ros antibody; Proto oncogene tyrosine protein kinase ros antibody; Proto oncogene tyrosine protein kinase ros precursor antibody; Proto-oncogene c-ros-1 antibody; Proto-oncogene tyrosine-protein kinase ros antibody; Receptor tyrosine kinase c ros oncogene 1 antibody; ros 1 antibody; ros 1C antibody; ros antibody; ros proto oncogene 1 , receptor tyrosine kinase antibody; ros_HUMAN antibody; ros1 antibody; ros1C antibody; Transmembrane tyrosine specific protein kinase antibody; v ros avian UR2 sarcoma virus oncogene homolog 1 antibody; v ros UR2 sarcoma virus oncogene homolog 1 antibody;
Cat. No.: HY-P702714
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ros1; Proto-oncogene C-ros-1; ros Proto-oncogene 1, Receptor Tyrosine Kinase; V-ros UR2 Sarcoma Virus oncogene Homolog 1 (Avian); MCF3; ros Proto-oncogene 1 , Receptor Tyrosine Kinase; ros; Transmembrane Tyrosine-Specific Protein Kinase; C-ros-1; Receptor
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705880
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ros1; Proto-oncogene C-ros-1; ros Proto-oncogene 1, Receptor Tyrosine Kinase; V-ros UR2 Sarcoma Virus oncogene Homolog 1 (Avian); MCF3; ros Proto-oncogene 1 , Receptor Tyrosine Kinase; ros; Transmembrane Tyrosine-Specific Protein Kinase; C-ros-1; Receptor
Species:
Human
Source:
sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
