1 Result for "

cardiac-specific myosin

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "cardiac-specific myosin" in MCE Product Catalog:

Cat. No.: HY-163120
CAS No.: 849011-39-8
Target:  

Myosin

Research Areas:  

Cardiovascular Disease

Myosin-IN-1 (compound F10) is a Myosin inhibitor that specifically targets cardiac myosin. Myosin-IN-1 stabilizes the biochemical and structural closed state of the cardiac myosin motor domain and reduces myocardial force production and calcium sensitivity in vitro. Myosin-IN-1 acts as a negative inotropic agent in isolated Langendroff-perfused rat hearts, reducing stress in isolated myofilaments and left ventricular pressure development. Myosin-IN-1 can be used in heart failure research .
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