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chloroquine resistance

" in MedChemExpress (MCE) Product Catalog:
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Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-17036

    Parasite Infection
    Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia, including resistance of P. falciparum to Chloroquine .
    Naphthoquine phosphate
  • HY-175493

    Parasite Infection
    CRT-IN-1 (compound 6x) is a potent chloroquine resistance transporter (CRT) inhibitor with an IC50 of 0.33 μM. CRT-IN-1 has activity .
    CRT-IN-1
  • HY-180373

    Parasite Infection
    WR 30090 (Compound 37) is a broad-spectrum antimalarial agent that does not rely on the classical antifolate pathway. WR 30090 exhibits strong activity against a variety of chloroquine-sensitive and resistant Plasmodium falciparum strains, especially the highly resistant Vietnamese strain. WR 30090 shows high activity in mouse malaria tests, with a minimum effective dose of 5 mg/kg and a minimum cure dose of 20 mg/kg. WR 30090 can be used for research on acute malaria .
    WR 30090

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