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3 Results for "
class III antiarrhythmic activity
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "class III antiarrhythmic activity" in MCE Product Catalog:
Cat. No.: HY-19049
CAS No.: 125883-03-6
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CK-1649 chloride is a class III antiarrhythmic agent. CK-1649 chloride can inhibit potassium channel activity .
Cat. No.: HY-182646
CAS No.: 149889-02-1
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NE-10133 is a ISK and IKS potassium channel (Potassium Channel) inhibitor. NE-10133 inhibits voltage-dependent and slowly activated delayed rectifier potassium currents. NE-10133 exhibits class III antiarrhythmic activity. NE-10133 is applicable for research related to arrhythmias .
Cat. No.: HY-124940
CAS No.: 446877-42-5
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Research Areas:
CPU-228 is a complex class III antiarrhythmic agent. CPU-228 concentration-dependently blocks the activities of the rapid component 50 of the delayed rectifier potassium channel (IKr) and the L-type calcium channel (ICa,L), with an IC50 value of 0.909 μM for ICa,L current. CPU-228 produces negative inotropic effects and induces mild, non-frequency-dependent prolongation of the effective refractory period (ERP) in isolated left atria. CPU-228 reduces the incidence of torsades de pointes (TDP) in anesthetized rabbits and inhibits ischemia/reperfusion-induced arrhythmias in rats. CPU-228 can be used in studies related to torsades de pointes .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
