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copper-catalyzed

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1904

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122

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97

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18

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21

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55

Isotope-Labeled Compounds

1434

Click Chemistry

128

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1

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W021042
    Tris(3-hydroxypropyltriazolylmethyl)amine
    2 Publications Verification

    THPTA

    		 Biochemical Assay Reagents Others
    Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA) is an accelerating ligand in the copper-catalyzed azide-alkyne cycloaddition reaction (CuAAC) and protects cells from oxidants generated by copper-catalyzed reduction of oxygen by ascorbate. In addition, Tris(3-hydroxypropyltriazolylmethyl)amine can also protect the histidine moiety of biomolecules in a manner proportional to the ligand concentration .
    Tris(3-hydroxypropyltriazolylmethyl)amine
  • HY-15680
    O-Propargyl-Puromycin
    25+ Cited Publications

    		 Biochemical Assay Reagents Others
    O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    O-Propargyl-Puromycin
  • HY-12008
    Erlotinib Hydrochloride
    Maximum Cited Publications
    134 Publications Verification

    CP-358774 hydrochloride; NSC 718781 hydrochloride; OSI-774 hydrochloride

    		 EGFR Autophagy Cancer
    Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib Hydrochloride
  • HY-151857
    TAMRA azide, 5-isomer
    1 Publications Verification

    		 Fluorescent Dye Others
    TAMRA azide, 5-isomer is a click chemical containing azide groups that can be used as a linker for TAMRA. The azide group of TAMRA Azide, 5-isomer enables copper-catalyzed click chemical reactions with alkynes, DBCO, and BCN . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups (Ex/Em = 555/580 nm).
    TAMRA azide, 5-isomer
  • HY-15458
    SAR131675
    5+ Cited Publications

    		 VEGFR Cancer
    SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    SAR131675
  • HY-W040124
    DL-Propargylglycine
    2 Publications Verification

    		 Amino Acid Derivatives Others
    DL-Propargylglycine is a Glycine (HY-Y0966) derivative . DL-Propargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    DL-Propargylglycine
  • HY-138749
    Biotin alkyne
    1 Publications Verification

    		 PROTAC Linkers Cancer
    Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin alkyne
  • HY-W011210
    Fmoc-Pra-OH

    		Amino Acid Derivatives Others
    Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Fmoc-Pra-OH
  • HY-15388
    Tazarotene
    2 Publications Verification

    AGN 190168

    		 RAR/RXR Autophagy Inflammation/Immunology Cancer
    Tazarotene (AGN 190168) is a selective retinoic acid receptor (RAR) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Tazarotene
  • HY-D1314
    FAM azide, 6-isomer

    6-FAM azide

    		 Fluorescent Dye Others
    FAM azide, 6-isomer (6-FAM azide) is a 6-carboxyfluorescein derivative with an azide functional group and coupling partner in copper-catalyzed azide-alkyne cycloaddition. FAM azide, 6-isomer participates in synthesis of fluorescently tagged disparlure enantiomers for pheromone-binding protein binding assays. FAM azide, 6-isomer is widely used for labeling oligonucleotides (Ex/Em = 493/517 nm) .
    FAM azide, 6-isomer
  • HY-100949
    EC330
    5+ Cited Publications

    		 Interleukin Related Biochemical Assay Reagents Cancer
    EC330 is a leukemia inhibitory factor (LIF) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    EC330
  • HY-140335
    Alkynyl myristic acid
    4 Publications Verification

    		 PROTAC Linkers Cancer
    Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Alkynyl myristic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkynyl myristic acid
  • HY-A0285
    Norethisterone enanthate

    Norigest

    		 Progesterone Receptor Endocrinology
    Norethisterone enanthate is a long-acting parenteral progestogen. Norethisterone enanthate is orally active . Norethisterone enanthate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norethisterone enanthate
  • HY-B1710
    Norethindrone acetate

    19-Norethindrone acetate

    		 Progesterone Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Norethindrone acetate is a female hormone used for the research of endometriosis . Norethindrone acetate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Norethindrone acetate
  • HY-102033
    Oxamflatin
    1 Publications Verification

    Metacept-3

    		 HDAC Cancer
    Oxamflatin (Metacept-3) is a potent HDAC inhibitor with an IC50 of 15.7 nM. Oxamflatin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Oxamflatin
  • HY-D1321
    Cy 5 amine hydrochloride
    1 Publications Verification

    Cyanine5 amine hydrochloride

    		 Fluorescent Dye Others
    Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) .
    Cy 5 amine hydrochloride
  • HY-P6438
    Alkyne-cRGD

    		Integrin Others Cancer
    Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction .
    Alkyne-cRGD
  • HY-15964
    Tirasemtiv
    1 Publications Verification

    CK-2017357

    		 Biochemical Assay Reagents Neurological Disease
    Tirasemtiv is an activator of the fast skeletal muscle troponin complex. Tirasemtiv is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Tirasemtiv
  • HY-W008395
    Fmoc-D-Pra-OH

    		Amino Acid Derivatives Others
    Fmoc-D-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-D-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Fmoc-D-Pra-OH
  • HY-D1320
    Cyanine5 azide chloride

    		Fluorescent Dye Others
    Cyanine5 azide chloride is a potent fluorescent dye. Cyanine5 azide chloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Cyanine5 azide chloride
  • HY-B1012
    Quinestrol

    W-3566

    		 Estrogen Receptor/ERR Endocrinology Cancer
    Quinestrol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Quinestrol
  • HY-D1588
    BODIPY-X-Alkyne

    		Fluorescent Dye Others
    BODIPY-X-Alkyne is an alkyne-modified BODIPY derivative (Ex=526 nm, Em=540 nm). BODIPY-X-Alkyne can react with azides via a copper-catalyzed click reaction .
    BODIPY-X-Alkyne
  • HY-107362
    CH7057288

    		Trk Receptor Cancer
    CH7057288 is a potent and selective TRK inhibitor. CH7057288 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    CH7057288
  • HY-43614
    Propynol Ethoxylate

    		PROTAC Linkers Cancer
    Propynol Ethoxylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propynol Ethoxylate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propynol Ethoxylate
  • HY-115495
    6-Alkynyl fucose

    		Biochemical Assay Reagents Others
    6-Alkynyl fucose is a tool in the study of protein O-fucosylation . 6-Alkynyl fucose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    6-Alkynyl fucose
  • HY-101603
    Manitimus

    FK778

    		 Biochemical Assay Reagents Inflammation/Immunology
    Manitimus is an inhibitor of dehydroorotate dehydrogenase, and a potent immunosuppressive agent. Manitimus is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Manitimus
  • HY-10249D
    AKT Kinase Inhibitor hydrochloride
    15+ Cited Publications

    		 Akt Cancer
    AKT Kinase Inhibitor hydrochloride is an Akt kinase inhibitor with anti-tumor activity . AKT Kinase Inhibitor (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    AKT Kinase Inhibitor hydrochloride
  • HY-B0110
    Gestodene

    SHB 331; WL 70

    		 Progesterone Receptor Endocrinology
    Gestodene(SHB 331;WL 70) is a progestin-based contraceptive. Gestodene is a click chemistry reagent. It contains an alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an azide group .
    Gestodene
  • HY-114507
    Flumioxazin

    Sumisoya; V-53482

    		 Environmental Pollutants Herbicide Others
    Flumioxazin (Sumisoya) is an herbicide for use in soybean and peanut. Flumioxazin inhibits the enzyme protoporphyrinogen oxidase . Flumioxazin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Flumioxazin
  • HY-145016
    HN37

    		Potassium Channel Neurological Disease
    HN37 as a potent and chemically stable antiepileptic agent candidate, with an EC50 of 37 nM for KCNQ2 . HN37 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    HN37
  • HY-50713
    Calcium-Sensing receptor antagonist I

    		CaSR Others
    Calcium-Sensing receptor antagonist I is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Calcium-Sensing receptor antagonist I
  • HY-155639
    Tyramide alkyne
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction. Tyramide alkyne can be used for ascorbate peroxidase 2 (APEX2) labeling .
    Tyramide alkyne
  • HY-119532
    Nordeprenyl

    Desmethylselegiline

    		 Drug Metabolite Metabolic Disease
    Nordeprenyl is the metabolite of Deprenyl. Deprenyl is a potent, selective and irreversible inhibitor of MAO-B . Nordeprenyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Nordeprenyl
  • HY-79584
    Propargyl-Tos

    		ADC Linker Cancer
    Propargyl-Tos is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-Tos is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-Tos
  • HY-W007319
    Phenylpropiolic acid

    		Endogenous Metabolite Metabolic Disease
    Phenylpropiolic acid is an endogenous metabolite. Phenylpropiolic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Phenylpropiolic acid
  • HY-160652
    17-Azidoheptadecanoic acid

    		Biochemical Assay Reagents Others
    17-Azidoheptadecanoic acid is a fatty acid azide with an azide linker. 17-Azidoheptadecanoic acid can undergo copper-catalyzed click chemistry reactions with alkynes, DBCO, and BCN for protein modification .
    17-Azidoheptadecanoic acid
  • HY-136554
    WYC-210

    		Drug Derivative Cancer
    WYC-210, a Tazarotene derivative, is a retinoid compound with lower anticancer activity . WYC-210 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    WYC-210
  • HY-151212
    BCP-T.A

    		Ferroptosis Glutathione Peroxidase Cancer
    BCP-T.A, a tunable heterocyclic electrophile, is a potent ferroptosis inducer by binding to GPX4 . BCP-T.A is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    BCP-T.A
  • HY-151647
    3-Azidopropanoic acid-PFP ester

    		Biochemical Assay Reagents Others
    3-Azidopropanoic acid-PFP ester is an azidopropanoic acid linker that contains an activated PFP ester. The azide group can undergo copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to form triazole linkages. The activated PFP ester can react with amine groups to form stable amide bonds . 3-Azidopropanoic acid-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    3-Azidopropanoic acid-PFP ester
  • HY-B1089
    Ethynodiol diacetate

    Ethynodiol acetate

    		 Progesterone Receptor Endocrinology
    Ethynodiol diacetate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ethynodiol diacetate
  • HY-147420
    Xelaglifam

    IDG-16177

    		 Free Fatty Acid Receptor Metabolic Disease
    Xelaglifam is a potent GPR40 agonist. Antihyperglycaemic activity . Xelaglifam is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Xelaglifam
  • HY-W051612A
    DL-Propargylglycine sodium
    2 Publications Verification

    		 Amino Acid Derivatives Biochemical Assay Reagents Others
    DL-Propargylglycine sodium is a Glycine (HY-Y0966) derivative. DL-Propargylglycine sodium is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    DL-Propargylglycine sodium
  • HY-12008A
    Erlotinib mesylate

    CP-358774 mesylate; NSC 718781 mesylate; OSI-774 mesylate

    		 EGFR Autophagy Cancer
    Erlotinib mesylate (CP-358774 mesylate) inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib mesylate
  • HY-111430
    1-Ethynylnaphthalene

    		Cytochrome P450 Cancer
    1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 1B1. 1-Ethynylnaphthalene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    1-Ethynylnaphthalene
  • HY-N3114
    Panaxydiol

    		Histamine Receptor Inflammation/Immunology
    Panaxydiol exhibits histamine-release inhibition activity . Panaxydiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Panaxydiol
  • HY-148793
    Resencatinib

    		c-Met/HGFR Cancer
    Resencatinib is a potent tyrosine kinase inhibitor with antineoplastic activity . Resencatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Resencatinib
  • HY-105102
    Netivudine

    882C87

    		 Nucleoside Antimetabolite/Analog HSV Infection
    Netivudine is a nucleoside analogue with potent anti-varicella zoster virus activity. Netivudine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Netivudine
  • HY-W051612
    DL-Propargylglycine hydrochloride

    		Amino Acid Derivatives Others
    DL-Propargylglycine hydrochloride is a Glycine (HY-Y0966) derivative. DL-Propargylglycine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
    DL-Propargylglycine hydrochloride
  • HY-147621
    FGFR-IN-6

    		FGFR Cancer
    FGFR-IN-6 (Compound 5) is a FGFR inhibitor . FGFR-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    FGFR-IN-6
  • HY-147052
    Boc-Pip-butyn

    		PROTAC Linkers Cancer
    Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker . Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Boc-Pip-butyn

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