1044589-82-3
Chemical Structure
NITD008
Synonym(s): 7-Deaza-2'-C-acetylene-adenosine
- CAS No.: 1044589-82-3
- Formula:C13H14N4O4
- Molecular Weight:290.27
IUPAC Name: (2R,3R,4R,5R)-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
InChIKey: NKRAIOQPSBRMOV-NRMKKVEVSA-N
SMILES: O[C@@]1(C#C)[C@H](N2C=CC3=C(N)N=CN=C32)O[C@H](CO)[C@H]1O
Biological Activity: NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM. NITD008 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NITD008 | 98.00% | NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM. NITD008 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||||||||||||||||||||
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Similarity Score 0.86
HY-10244RMK-0608 (Standard) -
Similarity Score 0.79
HY-1524752’-β-C-Ethynyladenosine -
Similarity Score 0.77
HY-100126Tubercidin -
Similarity Score 0.76
![4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152818.gif)
HY-1528184-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine -
Similarity Score 0.74
HY-1786322'-O-Me-7-deaza-rA -
Similarity Score 0.73
![4-Amino-5-iodo-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152819.gif)
HY-1528194-Amino-5-iodo-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine -
Similarity Score 0.73
HY-W0485137-Deaza-2'-deoxyadenosine -
Similarity Score 0.73
HY-162517UMM-766 -
Similarity Score 0.73
![7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Chemical Structure](//file.medchemexpress.com/product_pic/hy-152582.gif)
HY-1525827-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine -
Explore the MedChemAI to find more analogs
![4-Chloro-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152818.gif)
![4-Amino-5-iodo-7-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152819.gif)
![7-(3-Deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Chemical Structure](http://file.medchemexpress.com/product_pic/hy-152582.gif)
