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culture broth

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By Targets:	Acyltransferase (2) Aminopeptidase (1) Antibiotic (10) Apoptosis (1) Bacterial (13) Biochemical Assay Reagents (6) Drug Intermediate (1) Endogenous Metabolite (2) Fungal (3) Glutathione S-transferase (1) GSK-3 (1) HSP (1) Interleukin Related (1) Parasite (1) Reference Standards (1) STAT (1) Trk Receptor (1) β-catenin (1)
By Research Areas:	Cancer (8) Endocrinology (1) Infection (19) Inflammation/Immunology (1) Metabolic Disease (3) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101040

Telacebec Maximum Cited Publications 7 Publications Verification Q203; IAP6	Bacterial Antibiotic	Infection
Telacebec (Q203) is a midazopyridine amide compound. Telacebec is active against Mycobacterium tuberculosis H37Rv with an MIC₅₀ of 2.7 nM in culture broth medium.

HY-157355

Brain Heart Infusion Broth BHI	Biochemical Assay Reagents Bacterial	Infection
Brain Heart Infusion Broth (BHI) is a bacterial culture medium that can be used for microbial culture .

HY-157344

Nutrient Broth	Biochemical Assay Reagents	Others
Nutrient Broth is an important formula Broth medium and it can be used to culture microorganisms, bacteria and other organisms .

HY-125319

Amidepsine A	Acyltransferase	Metabolic Disease
Amidepsine A is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity .

HY-W295873

Cyclo(Phe-Gly) 1 Publications Verification	Bacterial	Infection Cancer
Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis .

HY-N14690

Piperazinomycin	Fungal Antibiotic Bacterial	Infection
Piperazinomycin is an antifungal and antibacterial antibiotic. Piperazinomycin is isolated from the culture broth of Streptoverticillium olivoreticuli subsp. neoenacticus. Piperazinomycin inhibits the growth of fungi, yeasts and some Mycobacterium species. Piperazinomycin exhibits inhibitory activity against Trichophyton species .

HY-117517

NG-012	Trk Receptor	Cancer
NG-012, potentiator of nerve growth factor (NGF), were isolated from the culture broth of Penicillium verruculosum F-4542. NG-012 potentiates the neurite outgrowth induced by NGF in rat pheochromocytoma cell line (PC12) .

HY-117738

Benarthin	Aminopeptidase Endogenous Metabolite GSK-3 β-catenin Apoptosis	Metabolic Disease
Benarthin is an orally active Pyroglutamyl peptidase inhibitor, THY1 inhibitor (with a K_d value of 5.13e-08 M) and competitive PGP-1 inhibitor (K_i = 1.2 µM). Benarthin is isolated from the culture broth of Streptomyces xanthophaeus MJ244-SF1. Benarthin disrupts the THY1-SFRP1 interaction, inhibits the activation of the GSK3α/β-β-catenin pathway, and reduces the upregulation of FASLG. Benarthin attenuates urothelial anoikis and reduces cell Apoptosis. Benarthin possesses iron-chelating activity. Benarthin maintains urothelial barrier integrity and blocks the pathological cascade of renal interstitial fibroblasts induced by HAP stimulation. Benarthin can be used in studies related to kidney stones .

HY-101040A

Telacebec ditosylate Q203 ditosylate; IAP6 ditosylate	Bacterial Antibiotic	Infection
Telacebec ditosylate is a midazopyridine amide compound. Telacebec ditosylate is active against Mycobacterium tuberculosis H37Rv with an MIC₅₀ of 2.7 nM in culture broth medium.

HY-B1921

Miocamycin Midecamycin acetate; Ponsinomycin	Bacterial	Infection
Miocamycin (Midecamycin acetate) is a derivative of midecamycin (HY-B1908), a macrolide antibiotic that can be isolated from a culture broth of Streptomyces mycarofaciens. Miocamycin has antibacterial properties .

HY-N9085

Neuchromenin	Bacterial	Neurological Disease
Neuchromenin is a microbial melabolite that can be isolated from the culture broth of Eupenicillium javanicum var. meloforme PFll81. Neuchromenin induces neurite outgrowth of PC12 cells .

HY-N12656

Versipelostatin	HSP	Cancer
Versipelostatin is a GRP78/Bip molecular chaperone down-regulator and can be isolated from the culture broth of Streptomyces versipellis 4083-SVS6 .

HY-N7307

Pachybasin	Bacterial	Infection
Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .

HY-Y0531

1-Adamantanol Tricyclo[3.3.1.1~3,7~]decan-1-ol	Drug Intermediate Bacterial	Infection
1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials .

HY-157351

E.Coli Broth	Biochemical Assay Reagents	Others
E.Coli Broth is a selectively concentrated broth that can be used to isolate, detect or culture E. coli.

HY-157373

Bromcresol Purple Broth Base	Biochemical Assay Reagents	Others
Bromcresol Purple Broth Base can be used for microbial culture .

HY-157361

Ethyl Violet Aziode Broth	Biochemical Assay Reagents	Others
Ethyl Violet Aziode Broth is a special medium for growth culture of streptococcus. The composition of 1 litre medium is 35.8 g Ethyl Violet Aziode Broth.

HY-172189

Sabouraud dextrose broth SDB	Biochemical Assay Reagents	Others
Sabouraud dextrose broth (SDB) can be used for the culture of molds and yeasts .

HY-114585A

Sperabillin A dihydrochloride	Glutathione S-transferase	Others
Sperabillin A (dihydrochloride)is new inhibitors ofglutathione S-transferaseisolated from the culture broth ofStreptomyces sp .

HY-114521

5-(4-Methoxyphenyl)oxazole	Parasite	Infection
5-(4'-Methoxyphenyl)-oxazole is a Caenorhabditis elegans hatch and growth inhibitor that isolated from fungal culture broth .

HY-129295

Amidepsine D	Acyltransferase	Metabolic Disease
Amidepsine D is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity .

HY-N14180

6-Deoxyilludin M	Antibiotic	Infection Cancer
6-Deoxyilludin M is an antitumor antibiotic possessing antileukemic activity. 6-Deoxyilludin M can be isolated from the culture broth of the Basidiomycota Pleurotus japonicas .

HY-N6181

Terrelumamide A	Others	Endocrinology
Terrelumamide A is a lumazine-containing peptide. Terrelumamide A is isolated from the culture broth of the marine-derived fungus Aspergillus terreus. Terrelumamide A exhibits pharmacological activity by improving insulin sensitivity. Terrelumamide A has the potential in the application of DNA sequence recognition .

HY-N15028

Depsidomycin	Antibiotic Bacterial	Infection Inflammation/Immunology
Depsidomycin is an immunomodulatory antibiotic with immunosuppressive activity that can be isolated from the culture broth of Streptomyces lavendofoliae MI951-62F2. Depsidomycin primarily exhibits antibacterial activity against Gram-positive bacteria .

HY-122191

AK-Toxin II	Others	Infection
AK-Toxin II is a phytotoxic metabolite that can be isolated from culture broth of alternaria alternata Japanese pear pathotype. AK-Toxin II induces characteristic veinal necrosis and rapid K ⁺ loss on susceptible pear leaves .

HY-125349

A-83016F	Antibiotic	Infection
A-83016F is an antibiotic. A-83016F has weak antimicrobial activity. A-83016F can be isolated from the culture broth of an unidentified actinomycete designated A83016 .

HY-126735

Saquayamycin D	Antibiotic Bacterial	Infection
Saquayamycin D is an antibiotic, which can be isolated from Streptomyces nodosus culture broth. Saquayamycin D exhibits antibacterial activity against various gram-positive bacteria with MIC of 12.5-50 μg/mL. Saquayamycin D inhibits the proliferation of Doxorubicin (HY-15142)-sensitive P388/S and Doxorubicin-resistant P388/ADR with IC₅₀ of 0.15 and 0.15 μg/mL .

HY-117092

BE-31405	Antibiotic Fungal	Infection
BE-31405 is an antifungal antibiotic. BE-31405 can be isolated from the culture broth of the fungal strains such as Penicillium minioluteum F31405, Talaromyces siamensis FKA-61, and Phomopsis sp. FKA-62. BE-31405 exhibits potent growth inhibitory activity against pathogenic fungal strains including Candida albicans, Candida glabrata, and Cryptococcus neoformans. BE-31405 shows no cytotoxicity against mammalian cells .

HY-P1708

Enopeptin A BRN 537924; NSC 657143	Bacterial	Infection
Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain. It is effective against Gram-positive bacteria, including methicillin-resistant S. aureus (MIC=25 μg/mL), and Gram-negative bacteria, including mutant forms of E. coli and P. aeruginosa (MICs=200 μg/mL); however, it is not inhibitory to fungi.

HY-117204

AA-57	Antibiotic	Infection
AA-57 is an acidic lipophilic antibiotic isolated from the fermentation broth of Actinomycetes strain AA-57. The AA-57 strain can be isolated from a soil sample collected in Koriyama City, Fukushima Prefecture, Japan. AA-57 has antibacterial properties against Gram-positive bacteria, Gram-negative bacteria, and acid-fast bacteria. AA-57 was discovered by screening actinomycete cultures for antibacterial properties. AA-57 exhibits significant antibacterial activity and has inhibitory effects against a variety of bacteria.

HY-N10237

Mycestericin C	Others	Cancer
Mycestericin C is a compound isolated from the culture broth of Mycelia sterilia ATCC 20349. Mycestericin C suppresses the proliferation of lymphocytes in the mouse allogeneic mixed lymphocyte reaction .

HY-N14778

N-Acetylisopenicillin N	Others	Others
N-Acetylisopenicillin N is isolated from the culture broth of Streptomyces tokunonensis sp. nov .

HY-N15263

Cepafungin III	Antibiotic Fungal	Infection Cancer
Cepafungin III is an acylpeptide antibiotic that can be isolated from the culture broth of Pseudomonas species. Cepafungin III exhibits inhibitory activity against yeast and fungi, and antitumor activity against P388 leukemia in mice, when mixed with Cepafungin I and II .

HY-W295873R

Cyclo(Phe-Gly) (Standard)	Bacterial Reference Standards	Infection Cancer
Cyclo(Phe-Gly) (Standard) is the analytical standard of Cyclo(Phe-Gly) (HY-W295873). This product is intended for research and analytical applications. Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis .

HY-N18989

Cyclo(L-Ile-D-Leu)	STAT Interleukin Related Endogenous Metabolite	Cancer
Cyclo (L-Ile-D-Leu) (Compound 15) is a STAT3 inhibitor. Cyclo (L-Ile-D-Leu) is isolated from the culture broth of Lactococcus lactis KR-050L. Cyclo (L-Ile-D-Leu) inhibits IL-6-induced STAT3 activation in cancer cells. Cyclo (L-Ile-D-Leu) is applicable to hepatocellular carcinoma research .

Brain Heart Infusion Broth BHI	Biochemical Assay Reagents
Brain Heart Infusion Broth (BHI) is a bacterial culture medium that can be used for microbial culture .

Nutrient Broth	Biochemical Assay Reagents
Nutrient Broth is an important formula Broth medium and it can be used to culture microorganisms, bacteria and other organisms .

1-Adamantanol Tricyclo[3.3.1.1~3,7~]decan-1-ol	Biochemical Assay Reagents
1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials .

E.Coli Broth	Biochemical Assay Reagents
E.Coli Broth is a selectively concentrated broth that can be used to isolate, detect or culture E. coli.

Bromcresol Purple Broth Base	Biochemical Assay Reagents
Bromcresol Purple Broth Base can be used for microbial culture .

Ethyl Violet Aziode Broth	Biochemical Assay Reagents
Ethyl Violet Aziode Broth is a special medium for growth culture of streptococcus. The composition of 1 litre medium is 35.8 g Ethyl Violet Aziode Broth.

Sabouraud dextrose broth SDB	Biochemical Assay Reagents
Sabouraud dextrose broth (SDB) can be used for the culture of molds and yeasts .

Amidepsine A	Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Phenols Metabolic Disease Disease Research Fields Source Classification	Acyltransferase
Amidepsine A is a fungal metabolite isolated from the culture broth of Humicola sp. FO-2942 that inhibits Diacylglycerol acyltransferases (DGAT) activity .

Cyclo(Phe-Gly) 1 Publications Verification	Infection Natural Products Classification of Application Fields Plants Compositae Disease Research Fields Source Classification Gueldenstaedtia verna (Georgi) Boriss. Cancer	Bacterial
Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis .

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culture broth

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Natural
Products