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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
cyclin-dependent kinase 9
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "cyclin-dependent kinase 9" in MCE Product Catalog:
41
41 Publications Verification
NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 μM, 0.706 μM, and 0.605 μM, respectively. NVP-2 induces cell apoptosis.
7
7 Cited Publications
Cat. No.: HY-16462
CAS No.: 1263369-28-3
CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8), has an IC50 of 5 nM and 7 nM in H929 multiple myeloma(MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively.
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1 Cited Publications
NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors .
Cat. No.: HY-176484
CDK9-IN-39 (1-7a-B1) is an orally active cyclin-dependent kinase 9 (CDK9) inhibitor with an IC50 of 6.51 nM. CDK9-IN-39 induces cell apoptosis by inhibiting the phosphorylation of RNA polymerase II at Ser2 and can be used for study of colorectal cancer .
Cat. No.: HY-P703558
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated kinase Complex Catalytic Subunit; Prev. CDC2L4; cyclin-dependent kinase 9 (CDC2-Related kinase); TAK; Serine/Threonine Protein kinase PITALRE; Cell Division Protein kinase 9; Serine/Threonine-Protein kinase PITALRE; cyclin-dependent K
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701374
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated kinase Complex Catalytic Subunit; Prev. CDC2L4; cyclin-dependent kinase 9 (CDC2-Related kinase); TAK; Serine/Threonine Protein kinase PITALRE; Cell Division Protein kinase 9; Serine/Threonine-Protein kinase PITALRE; cyclin-dependent K
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701377
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated kinase Complex Catalytic Subunit; Prev. CDC2L4; cyclin-dependent kinase 9 (CDC2-Related kinase); TAK; Serine/Threonine Protein kinase PITALRE; Cell Division Protein kinase 9; Serine/Threonine-Protein kinase PITALRE; cyclin-dependent K
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701376
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated kinase Complex Catalytic Subunit; Prev. CDC2L4; cyclin-dependent kinase 9 (CDC2-Related kinase); TAK; Serine/Threonine Protein kinase PITALRE; Cell Division Protein kinase 9; Serine/Threonine-Protein kinase PITALRE; cyclin-dependent K
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701375
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated kinase Complex Catalytic Subunit; Prev. CDC2L4; cyclin-dependent kinase 9 (CDC2-Related kinase); TAK; Serine/Threonine Protein kinase PITALRE; Cell Division Protein kinase 9; Serine/Threonine-Protein kinase PITALRE; cyclin-dependent K
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702689
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated kinase Complex Catalytic Subunit; Prev. CDC2L4; cyclin-dependent kinase 9 (CDC2-Related kinase); TAK; Serine/Threonine Protein kinase PITALRE; Cell Division Protein kinase 9; Serine/Threonine-Protein kinase PITALRE; cyclin-dependent K
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702690
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated kinase Complex Catalytic Subunit; Prev. CDC2L4; cyclin-dependent kinase 9 (CDC2-Related kinase); TAK; Serine/Threonine Protein kinase PITALRE; Cell Division Protein kinase 9; Serine/Threonine-Protein kinase PITALRE; cyclin-dependent K
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702988
Purity: ≥ 75%, as determined by reducing SDS-PAGE.
Synonyms: CDKL5; Serine/Threonine-Protein kinase 9; Prev. STK9; cyclin dependent kinase 5 Transcript; cyclin-dependent kinase-Like 5; DEE2; CFAP247; ISSX; EIEE2; cyclin dependent kinase Like 5; Serine/Threonine kinase 9
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P85098
Synonyms: CDK9; CDC2L4; TAK; cyclin-dependent kinase 9; C-2K; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; Serine/threonine-protein kinase PITALRE; Tat-associated kinase complex catalytic subunit
Cat. No.: HY-15163A
CAS No.: 1354567-82-0
Zotiraciclib hydrochloride is a novel small molecule multi-target enzyme inhibitor with activity in inhibiting tumor growth. Zotiraciclib hydrochloride exerts its anti-tumor effect by reducing the level of Myc through inhibiting cyclin-dependent kinase 9 (CDK9). Zotiraciclib hydrochloride may be useful for inhibiting cancers that cross the blood-brain barrier. The high protein level of MCL-1 of Zotiraciclib hydrochloride is associated with survival, suggesting that it may serve as a prognostic factor and inhibitory target in further studies .
Cat. No.: HY-P87922
Synonyms: CDC2L4, TAK, CDK9, cyclin-dependent kinase 9, C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE, Tat-associated kinase complex catalytic subunit
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
