1263369-28-3
1263369-28-3
Chemical Structure
CDK9-IN-2
- CAS No.: 1263369-28-3
- Formula:C23H25ClFN5
- Molecular Weight:425.93
IUPAC Name: N2'-((1r,4r)-4-aminocyclohexyl)-5'-chloro-N6-(3-fluorobenzyl)-[2,4'-bipyridine]-2',6-diamine
InChIKey: XKHXPTSUVPZYDW-IYARVYRRSA-N
SMILES: ClC1=CN=C(N[C@@H]2CC[C@@H](N)CC2)C=C1C3=NC(NCC4=CC(F)=CC=C4)=CC=C3
Biological Activity: CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8), has an IC50 of 5 nM and 7 nM in H929 multiple myeloma(MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively.
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CDK9-IN-2 | 98.72% | CDK9-IN-2 is a special cyclin-dependent kinase 9 (CDK9) inhibitor, extracted from patent WO/2012131594A1, compound CDKI(8), has an IC50 of 5 nM and 7 nM in H929 multiple myeloma(MM) cell line (72 hours) and A2058 skin cell line (72 hours), respectively. | ||||||||||||||||||||
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Keywords
