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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
cyclinT1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "cyclinT1" in MCE Product Catalog:
3
Riviciclib hydrochloride (P276-00) is a potent cyclin-dependent kinase (CDK) inhibitor, which inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively [1] .
Riviciclib hydrochloride (P276-00) shows antitumor activity on cisplatin-resistant cells .
Cat. No.: HY-16559A
CAS No.: 920113-02-6
Synonyms: P276-00 free base
Riviciclib (P276-00 free base) is a potent cyclin-dependent kinase (CDK) inhibitor, which inhibits CDK9-cyclinT1, CDK4-cyclin D1, and CDK1-cyclinB with IC50s of 20 nM, 63 nM, and 79 nM, respectively [1] .
Riviciclib shows antitumor activity on cisplatin-resistant cells .
Cat. No.: HY-149495
CP-07 is a selective flavonoid-based PROTAC degrader that targets and degrades CDK9. CP-07 exhibits an IC50 of 3.3 nM against CDK9/cyclin T1, and induces CDK9 degradation in a concentration-dependent manner in 22RV1 cells with a DC50 of 43 nM. CP-07 rapidly triggers ligand-dependent and proteasome-dependent degradation of CDK9. CP-07 can be applied in prostate cancer-related research [1].
Cat. No.: HY-P703098
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCNT1; Cyclin-T1; Prev. HIVE1; Cyclin C-Related Protein; CYCT1; MLLT10/CCNT1 Fusion; CCNT; Cyclin-T; Human Immunodeficiency Virus Type 1 (HIV-1) Expression (Elevated) 1; CycT1; Cyclin T1; CDK9-Associated C-Type Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-P701376
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated Kinase Complex Catalytic Subunit; Prev. CDC2L4; Cyclin-Dependent Kinase 9 (CDC2-Related Kinase); TAK; Serine/Threonine Protein Kinase PITALRE; Cell Division Protein Kinase 9; Serine/Threonine-Protein Kinase PITALRE; Cyclin-Dependent K
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
