61 Results for "

desthiobiotin

" in MedChemExpress (MCE) Product Catalog:
Products (61)

61 Results for "desthiobiotin" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-150230
CAS No.: 2924824-04-2
Purity:  99.51%
Target:  

ADC Linkers

Research Areas:  

Cancer

Desthiobiotin-Iodoacetamide can be used as an ADC Linker. Desthiobiotin-Iodoacetamide also acts as a probe used to label the the Oridonin (HY-N0004)-treated cell lysis .
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1
1 Cited Publications
Cat. No.: HY-143205
Purity:  97.73%
Synonyms: IA-DTB
Research Areas:  

Cancer

Desthiobiotin polyethyleneoxide iodoacetamide is useful for cysteine labeling in chemoproteomic experiments .
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Cat. No.: HY-128699
CAS No.: 533-48-2
Purity:  99.89%
Synonyms: Dethiobiotin
D-Desthiobiotin is a biotin derivative. D-Desthiobiotin increases testosterone. D-Desthiobiotin is used in affinity chromatography and protein chromatography, also can be used for protein and cell labeling, detection and isolation .
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Cat. No.: HY-P11307
CAS No.: 1334608-28-4
Target:  

Proteasome

Research Areas:  

Cancer

Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma .
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Cat. No.: HY-P11306
CAS No.: 247068-92-4
Target:  

Proteasome NF-κB

Research Areas:  

Inflammation/Immunology

Biotin-(Oaa)3-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)3-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain .
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Cat. No.: HY-134722
Purity:  ≥95.0%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Hydrazide-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-W437745
CAS No.: 80750-24-9
Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .
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Cat. No.: HY-W096120
CAS No.: 1426828-06-9
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG3-Desthiobiotin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-134720
CAS No.: 2306109-91-9
Purity:  99.23%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Amine-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-134721
CAS No.: 2237234-71-6
Purity:  99.87%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-W190908A
Desthiobiotin-PEG4-NHS ester is a PEG derivative composed of desthiobiotin, 4 PEG units, and NHS ester. NHS ester can be conjugated to amino acids or other molecules containing amino groups.
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Cat. No.: HY-P10620
Target:  

Bacterial

Research Areas:  

Others

GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .
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Cat. No.: HY-P10244F
Target:  

Inhibitory Antibodies

Research Areas:  

Infection

Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1 .
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Cat. No.: HY-P2546
CAS No.: 87468-58-4
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
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Cat. No.: HY-P3576A
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .
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Cat. No.: HY-140301
CAS No.: 2032788-37-5
Purity:  96.41%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-Desthiobiotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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Cat. No.: HY-P10886
CAS No.: 1465809-36-2
Research Areas:  

Inflammation/Immunology

Zifogaptide is a gap junction protein channel regulator. Zifogaptide mimics the PDZ-binding motif at the C-terminal of Claudin C and competitively interferes with the interaction between Claudin–TJP1 (ZO-1) scaffold. Zifogaptide can promote epithelial cell migration, reduce scar formation, and accelerate wound healing. Zifogaptide can be used for radiation dermatitis, skin injuries, etc .
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Cat. No.: HY-P5351A
Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .
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Cat. No.: HY-P2491
CAS No.: 1815618-06-4
Target:  

Fluorescent Dye

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .
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Cat. No.: HY-P2136F
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .
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