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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
general control nonderepressible 2
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "general control nonderepressible 2" in MCE Product Catalog:
27
27 Cited Publications
Research Areas:
GCN2-IN-1 is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of <0.3 μM in the enzyme assay and an IC50 of 0.3-3 μM in the cell assay .
2
2 Cited Publications
Research Areas:
GCN2-IN-7 (compound 39) is an orally active and selective general control nonderepressible 2 (GCN2) inhibitor (IC50=5 nM). GCN2-IN-7 shows anti-tumor activity in vivo .
Cat. No.: HY-P705590
Synonyms: EIF2AK4; Eukaryotic Translation Initiation Factor 2-Alpha Kinase 4; Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4; Non-Specific Serine/Threonine Protein Kinase; GCN2; general control nonderepressible 2; KIAA1338; GCN2 EIF2alpha Kinase; EIF-2-A
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-208758A
CAS No.: 1627177-37-0
Research Areas:
(S)-GCN2-IN-8 is a general control nonderepressible 2 (GCN2, EIF2AK4) inhibitor. (S)-GCN2-IN-8 inhibits signal transduction by the stress response kinase GCN2. (S)-GCN2-IN-8 can be used for the research of cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
