2396465-33-9
2396465-33-9
Chemical Structure
GCN2-IN-7
- CAS No.: 2396465-33-9
- Formula:C22H23BrN8OS
- Molecular Weight:527.44
IUPAC Name: (1R,3R)-3-((3-bromo-1-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)-N,1-dimethylcyclopentane-1-carboxamide
InChIKey: ASGMFNBUXDJWJJ-JLCFBVMHSA-N
SMILES: O=C([C@@]1(C)C[C@H](NC2=NC=C3C(N(C4=CC=C(C5=NN=C(C)S5)C=C4)N=C3Br)=N2)CC1)NC
Biological Activity: GCN2-IN-7 (compound 39) is an orally active and selective general control nonderepressible 2 (GCN2) inhibitor (IC50=5 nM). GCN2-IN-7 shows anti-tumor activity in vivo[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GCN2-IN-7 | 99.92% | GCN2-IN-7 (compound 39) is an orally active and selective general control nonderepressible 2 (GCN2) inhibitor (IC50=5 nM). GCN2-IN-7 shows anti-tumor activity in vivo. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-175877RAPT-37-Me -
Similarity Score 0.47
HY-208758GCN2/GSK3α-IN-1 -
Similarity Score 0.47
HY-208758AGCN2-IN-8 -
Similarity Score 0.46
HY-13497STK33-IN-1 -
Similarity Score 0.45
HY-156706JAK-IN-31 -
Similarity Score 0.44
HY-109963PR5-LL-CM01 -
Similarity Score 0.43
HY-124652TBK1/IKKε-IN-4 -
Similarity Score 0.43
HY-159613PELP1-IN-1 -
Similarity Score 0.43
HY-183042p38α-IN-12 -
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