JAK-IN-31
JAK-IN-31 (Example 75) is a JAK inhibitor with IC50 ranges of ≤0.01µM, ≤0.01µM, 0.01-0.1 µM and ≤0.01µM for JAK1, JAK2, JAK3 and Tyk2 respectively. JAK-IN-31 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2597016-88-9
- Formula: C21H19N7O2S2
- Molecular Weight:465.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 2597016-88-9
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Molecular Weight 465.55
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Formula C21H19N7O2S2
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SMILES
CC1=NN=C(S1)C2=CN=C3C(C=CN3)=C2N[C@@H]4C[C@@H](C4)NS(=O)(C5=CC(C#N)=CC=C5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)