1448693-69-3
Chemical Structure
GCN2-IN-1
- CAS No.: 1448693-69-3
- Formula:C19H18N10O
- Molecular Weight:402.41
IUPAC Name: 3-(1H-indazol-6-yl)-N-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine
InChIKey: CFNFLNGJQOHNPR-UHFFFAOYSA-N
SMILES: C1(NC2=CN(C3CCOCC3)N=C2)=NC=C(N=NN4C5=CC6=C(C=C5)C=NN6)C4=N1
Biological Activity: GCN2-IN-1 is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of <0.3 μM in the enzyme assay and an IC50 of 0.3-3 μM in the cell assay[1].
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GCN2-IN-1 | 99.46% | GCN2-IN-1 is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of <0.3 μM in the enzyme assay and an IC50 of 0.3-3 μM in the cell assay. | ||||||||||||||||||||
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Keywords