Search Result

Results for "

guanidine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adrenergic Receptor (2) Amino Acid Derivatives (1) AMPK (2) Autophagy (2) Bacterial (3) Biochemical Assay Reagents (5) DNA/RNA Synthesis (1) Drug Intermediate (1) Endogenous Metabolite (7) Exosomes (2) Fluorescent Dye (2) GABA Receptor (1) Histamine Receptor (1) Imidazoline Receptor (2) Isotope-Labeled Compounds (6) Liposome (1) Parasite (1) Reactive Oxygen Species (ROS) (1) Reference Standards (4) Sigma Receptor (2) Sodium Channel (3) SphK (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (1) Infection (7) Inflammation/Immunology (3) Metabolic Disease (8) Neurological Disease (6)

By Targets:

5-HT Receptor (1)

Adrenergic Receptor (2)

Amino Acid Derivatives (1)

AMPK (2)

Autophagy (2)

Bacterial (3)

Biochemical Assay Reagents (5)

DNA/RNA Synthesis (1)

Drug Intermediate (1)

Endogenous Metabolite (7)

Exosomes (2)

Fluorescent Dye (2)

GABA Receptor (1)

Histamine Receptor (1)

Imidazoline Receptor (2)

Isotope-Labeled Compounds (6)

Liposome (1)

Parasite (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (4)

Sigma Receptor (2)

Sodium Channel (3)

SphK (1)

By Research Areas:

Cancer (9)

Cardiovascular Disease (1)

Infection (7)

Inflammation/Immunology (3)

Metabolic Disease (8)

Neurological Disease (6)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15435

CHAPS 4 Publications Verification	Exosomes Biochemical Assay Reagents	Others
CHAPS is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm-Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS is commonly used in research on the separation and purification of membrane proteins .

HY-B0178A

Guanidine hydrochloride 3 Publications Verification Guanidinium chloride; Aminoformamidine hydrochloride	Autophagy Endogenous Metabolite	Metabolic Disease Cancer
Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

HY-121360

Cylindrospermopsin	DNA/RNA Synthesis Reactive Oxygen Species (ROS)	Cancer
Cylindrospermopsin, a cyanotoxin, is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA. Cylindrospermopsin induces hepatocellular hypertrophy, renal cellular hypertrophy, intracellular reactive oxygen species (ROS), DNA strand breaks, mitochondrial hyperpolarisation, ultrastructural damage, and altered gene expression in liver, kidney, and intestinal cells. Cylindrospermopsin can be used in research including hepatocellular carcinoma and water quality testing .

HY-59156

Triazabicyclodecene	Drug Intermediate	Others
Triazabicyclodecene is a bicyclic guanidine compound that can serve as a pharmaceutical intermediate for the formation of amides or esters .

HY-15435A

CHAPS hydrate 4 Publications Verification	Biochemical Assay Reagents Exosomes	Others
CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .

HY-W250727

TNS sodium 1 Publications Verification 6-(p-Tolylamino)naphthalene-2-sulfonate sodium	Fluorescent Dye	Others
TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .

HY-N0930B

Galegine hydrochloride	AMPK Bacterial	Infection Metabolic Disease
Galegine hydrochloride, a guanidine derivative, contributes to weight loss in mice. Guanidine hydrochloride is the compound derived from G. officinalis, which gave rise to the biguanides, metformin and phenformin. Galegine hydrochloride activates AMPK in 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hydrochloride has antibacterial activity, with minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains .

HY-107757

GMQ hydrochloride 2-guanidine-4-methylquinazoline hydrochloride	Sodium Channel	Neurological Disease
GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC₅₀ value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research .

HY-D0841

Guanidine thiocyanate 3 Publications Verification	Endogenous Metabolite	Infection Cancer
Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction .

HY-N0930A

Galegine hemisulfate	AMPK Bacterial	Infection Metabolic Disease
Galegine hemisulfate, a guanidine derivative, contributes to weight loss in mice. Galegine hemisulfate activates AMPK in 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hemisulfate has antibacterial activity, with minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains .

HY-B0178B

*6M Guanidine* hydrochloride Solution** 6M Guanidinium chloride Solution; 6M Aminoformamidine hydrochloride Solution	Biochemical Assay Reagents	Others
6M Guanidine hydrochloride Solution (6M Guanidinium chloride Solution) is a strong protein denaturant. 6M Guanidine hydrochloride Solution causes proteins to assume a random coil conformation .

HY-100939

4-Chlorophenylguanidine hydrochloride	Sodium Channel	Neurological Disease
4-Chlorophenylguanidine hydrochloride is an urokinase-type plasminogen activator inhibitor. 4-Chlorophenylguanidine hydrochloride is a potent ASIC3 positive allosteric modulator and reverses the effects of ASIC3 desensitization. 4-Chlorophenylguanidine hydrochloride influences ASIC3 activity through directly activating the channel and increasing proton sensitivity. 4-Chlorophenylguanidine hydrochloride offers a chemical backbone for the design of new ASIC3 ligands to study ASIC3 in vivo .

HY-W105860S

Guanidine-15N3 hydrobromide	Isotope-Labeled Compounds	Others
Guanidine Hydrobromide- ¹⁵N₃ is the ¹⁵N labeled Guanidine Hydrobromide[1].

HY-D0841R

Guanidine thiocyanate (Standard)	Endogenous Metabolite Reference Standards	Infection Cancer
Guanidine thiocyanate (Standard) is the analytical standard of Guanidine thiocyanate. This product is intended for research and analytical applications. Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction .

HY-B0178AS

Guanidine-13C,15N3 hydrochloride Guanidinium-13C,15N3 chloride; Aminoformamidine-13C,15N3 hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Guanidine- ¹³C, ¹⁵N₃ (hydrochloride)is the ¹³C-labeled and ¹⁵N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

HY-139226

GMQ 2-guanidine-4-methylquinazoline	GABA Receptor	Inflammation/Immunology
GMQ is an acid-sensing ion channel modulator, competitive GABA_AR antagonist. GMQ preferentially, potently, competitively inhibits GABAARs. GMQ inhibits α₁β₂, α₁β₂γ₂, α₄β₂γ₂ and α₅β₂γ₂ GABA_ARs. GMQ enhances neuronal excitation through inhibition of GABAergic transmission. GMQ has anti-histamine effects in the enteric system, inhibiting gastric acid secretion .

HY-47228

KB-5492 free base	Sigma Receptor	Inflammation/Immunology
KB-5492 free base is a potent and selective inhibitor of sigma receptor, inhibits specific [ ³H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC₅₀ of 3.15 μM. KB-5492 free base is an anti-ulcer agent .

HY-W710540

Guanidine-15N3 hydrochloride	Isotope-Labeled Compounds	Cancer
Guanidine- ¹⁵N₃ hydrochloride is the ¹⁵N-labeled Guanidine Hydrobromide (HY-W710540) .

HY-B0178AR

Guanidine hydrochloride (Standard) Guanidinium chloride (Standard); Aminoformamidine hydrochloride (Standard)	Autophagy Reference Standards Endogenous Metabolite	Metabolic Disease Cancer
Guanidine (hydrochloride) (Standard) is the analytical standard of Guanidine (hydrochloride). This product is intended for research and analytical applications. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

HY-B0178AS1

Guanidine-d5 hydrochloride Guanidinium-d5 chloride; Aminoformamidine-d5 hydrochloride	Endogenous Metabolite	Metabolic Disease
Guanidine-d₅ (hydrochloride) is the deuterium labeled Guanidine hydrochloride . Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

HY-W023072S

Agmatine-d8 dihydrochloride 1-(4-Aminobutyl)guanidine-d8 dihydrochloride	Isotope-Labeled Compounds	Others
Agmatine-d₈ (dihydrochloride) (1-(4-Aminobutyl)guanidine-d₈ (dihydrochloride)) is the deuterium labeled 1-(4-Aminobutyl)guanidine dihydrochloride (HY-W023072).

HY-105747A

Guanoxyfen nitrate N-(3-Phenoxypropyl)guanidine nitrate; (3-Phenoxypropyl)guanidine nitrate	Endogenous Metabolite	Infection Neurological Disease
Guanoxyfen (N-(3-Phenoxypropyl)guanidine) nitrate is a compound that exhibits potent inhibitory activity against the serine protease enzyme TMPRSS2, which plays a crucial role in the infectivity of coronaviruses. Guanoxyfen nitrate is also an effective inhibitor of vasoconstrictor responses to sympathetic nerve stimulation.

HY-106504

Aganodine	Imidazoline Receptor	Neurological Disease
Aganodine is a guanidine that activates presynaptic imidazoline receptors and can inhibit electrically evoked [ ³H]-norepinephrine release .

HY-W777037

*2,3-Dichlorobenzamidyl Guanidine-13C2*	Isotope-Labeled Compounds	Others
2,3-Dichlorobenzamidyl Guanidine- ¹³C₂ is the ¹³C-labeled 2-(2,3-Dichlorobenzoyl)hydrazine-1-carboximidamide (HY-W727201).

HY-W699749

Guanyl Urea hydrochloride-15N4	Isotope-Labeled Compounds	Others
Guanyl Urea hydrochloride- ¹⁵N₄ is the ¹⁵N labeled Carbamoyl-guanidine Amidino Urea (HY-W738276).

HY-N1051

Zarzissine	Bacterial	Infection Cancer
Zarzissine is a cytotoxic guanidine alkaloid that can be isolated from the Mediterranean sponge Anchinoe paupertas. Zarzissine shows antimicrobial and anticancer activities .

HY-124910

BU-E-75	Histamine Receptor Adrenergic Receptor	Cardiovascular Disease
BU-E-75 is a guanidine-type H₂ receptor agonist that exhibits antagonism at postsynaptic α-adrenoceptors, which can relax the noradrenaline-precontracted vessels .

HY-117868

NC-174 CP-Dpm-GA	Fluorescent Dye	Others
NC-174 is a super-strong guanidine compound that is sweeter than sucrose. NC-174 is more than 300,000 times sweeter than sucrose and has the potential to be a probe for sweet taste receptors .

HY-161325

Antileishmanial agent-26	Parasite	Infection
Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with anti-Leishmania donovani activity. Its IC₅₀ value against Leishmania donovani is 5.67 μM, and its CC₅₀ value against THP-1 is 3.79 μM. Antileishmanial agent-26 can be used in the research of tropical diseases .

HY-19120

KB-5492 anhydrous	Sigma Receptor	Inflammation/Immunology
KB-5492 anhydrous is a potent and selective inhibitor of sigma receptor, inhibits specific [ ³H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC₅₀ of 3.15 μM. KB-5492 anhydrous is an anti-ulcer agent .

HY-182988

L-Arg-DSPE	Liposome	Cancer
L-Arg-DSPE is an arginine-functionalized DSPE lipid containing free guanidine groups. L-Arg-DSPE serves as a component of NO-responsive degradable drug-loaded liposomal nanomotors (L-Arg@Lip-DOX), promoting drug deep tumor tissue penetration and cellular internalization. L-Arg-DSPE can be used for the research of drug delivery .

HY-WAA0304

Agmatine	5-HT Receptor Adrenergic Receptor Imidazoline Receptor	Neurological Disease
1-(4-Aminobutyl) guanidine (Agmatine) is an orally active analgesic that can cross the blood-brain barrier. 1-(4-Aminobutyl) guanidine targets the 5-HT_2A receptor, 5-HT₃ receptor, α₂-adrenergic receptor, and I1 imidazoline receptor. 1-(4-Aminobutyl) guanidine produces dose-dependent analgesic effects in various pain models. 1-(4-Aminobutyl) guanidine can be used in research related to visceral pain, neuropathic pain, and inflammatory pain .

HY-W012074R

Famotidine impurity 16 (Standard)	Reference Standards
2-(4-(((2-Cyanoethyl)thio)methyl)thiazol-2-yl)guanidine (Standard) is the analytical standard of 2-(4-(((2-Cyanoethyl)thio)methyl)thiazol-2-yl)guanidine. This product is intended for research and analytical applications.

HY-107757R

GMQ hydrochloride (Standard) 2-guanidine-4-methylquinazoline hydrochloride (Standard)	Reference Standards Sodium Channel	Neurological Disease
GMQ hydrochloride (Standard) is the analytical standard of GMQ (hydrochloride) (HY-107757). This product is intended for research and analytical applications. GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC₅₀ value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research .

HY-W845699

H-His-Arg-OH	Amino Acid Derivatives	Others
H-His-Arg-OH is a dipeptide containing guanidine groups. H-His-Arg-OH can be used as a dissociating agent to reduce the critical micelle concentration and form a stable nano lotion .

HY-P2768A

Leucine dehydrogenase, Bacillus sp.	Biochemical Assay Reagents	Metabolic Disease
Leucine dehydrogenase, Bacillus sp. (EC 1.4.1.9) is a carboxyl lyase that cleaves carbon-carbon bonds. L-Arginine Decarboxylase has one substrate, L-arginine, and two products, guanidine and CO2.

HY-E70998

L-Arginine Decarboxylase, Escherichia coli	Biochemical Assay Reagents	Metabolic Disease
L-Arginine Decarboxylase, Escherichia coli (EC 4.1.1.19) is a carboxyl lyase that cleaves carbon-carbon bonds. L-Arginine Decarboxylase has one substrate, L-arginine, and two products, guanidine and CO2.

HY-12896

SLR080811	SphK	Cancer
SLR080811 is a guanidine-based selective sphingosine kinase 2 (SphK2) inhibitor with a K_i of 1.3 μM, exhibiting ~10-fold selectivity over SphK1 (K_i = 12 μM). SLR080811 reduces sphingosine 1-phosphate (S1P) levels in vitro, but drives a SphK1-dependent increase in S1P in mice. SLR080811 can be used for cancers and fibrosis research .

Cat. No.	Product Name	Type

HY-59156

Triazabicyclodecene	Biochemical Assay Reagents
Triazabicyclodecene is a bicyclic guanidine compound that can serve as a pharmaceutical intermediate for the formation of amides or esters .

HY-15435A

CHAPS hydrate 4 Publications Verification	Biochemical Assay Reagents
CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .

CHAPS hydrate

4 Publications Verification

Biochemical Assay Reagents

CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .

HY-W250727

TNS sodium 1 Publications Verification 6-(p-Tolylamino)naphthalene-2-sulfonate sodium	Biochemical Assay Reagents
TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .

TNS sodium

1 Publications Verification

6-(p-Tolylamino)naphthalene-2-sulfonate sodium

Biochemical Assay Reagents

TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .

HY-D0841

Guanidine thiocyanate 3 Publications Verification	Biochemical Assay Reagents
Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction .

HY-B0178B

*6M Guanidine* hydrochloride Solution** 6M Guanidinium chloride Solution; 6M Aminoformamidine hydrochloride Solution	Biochemical Assay Reagents
6M Guanidine hydrochloride Solution (6M Guanidinium chloride Solution) is a strong protein denaturant. 6M Guanidine hydrochloride Solution causes proteins to assume a random coil conformation .

HY-D0841R

Guanidine thiocyanate (Standard)	Biochemical Assay Reagents
Guanidine thiocyanate (Standard) is the analytical standard of Guanidine thiocyanate. This product is intended for research and analytical applications. Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction .

Guanidine thiocyanate (Standard)

Biochemical Assay Reagents

Guanidine thiocyanate (Standard) is the analytical standard of Guanidine thiocyanate. This product is intended for research and analytical applications. Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction .

Cat. No.	Product Name	Target	Research Area

HY-W845699

H-His-Arg-OH	Amino Acid Derivatives	Others
H-His-Arg-OH is a dipeptide containing guanidine groups. H-His-Arg-OH can be used as a dissociating agent to reduce the critical micelle concentration and form a stable nano lotion .

HY-W845699A

H-His-Arg-OH acetate	Peptides	Others
H-His-Arg-OH acetate is a dipeptide containing guanidine groups. H-His-Arg-OH acetate can be used as a dissociating agent to reduce the critical micelle concentration and form a stable nano lotion .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0178A

Guanidine hydrochloride 3 Publications Verification Guanidinium chloride; Aminoformamidine hydrochloride	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Autophagy Endogenous Metabolite
Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

HY-121360

Cylindrospermopsin	Microorganisms Source Classification	DNA/RNA Synthesis Reactive Oxygen Species (ROS)
Cylindrospermopsin, a cyanotoxin, is a polycyclic uracil derivative containing guanidine and sulfate groups, which can inhibit protein synthesis and covalently modify DNA or RNA. Cylindrospermopsin induces hepatocellular hypertrophy, renal cellular hypertrophy, intracellular reactive oxygen species (ROS), DNA strand breaks, mitochondrial hyperpolarisation, ultrastructural damage, and altered gene expression in liver, kidney, and intestinal cells. Cylindrospermopsin can be used in research including hepatocellular carcinoma and water quality testing .

HY-N0930B

Galegine hydrochloride	Alkaloids Classification of Application Fields Leguminosae Other Alkaloids Metabolic Disease Plants Galega officinalis Linn. Disease Research Fields Source Classification	AMPK Bacterial
Galegine hydrochloride, a guanidine derivative, contributes to weight loss in mice. Guanidine hydrochloride is the compound derived from G. officinalis, which gave rise to the biguanides, metformin and phenformin. Galegine hydrochloride activates AMPK in 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hydrochloride has antibacterial activity, with minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains .

HY-D0841

Guanidine thiocyanate 3 Publications Verification	Infection Structural Classification Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction .

HY-D0841R

Guanidine thiocyanate (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Guanidine thiocyanate (Standard) is the analytical standard of Guanidine thiocyanate. This product is intended for research and analytical applications. Guanidine thiocyanate is a strong protein denaturant and potent inhibitor of nucleases. Guanidinium thiocyanate is a nucleic acid protector in the extraction of DNA and RNA from cells. Guanidine thiocyanate is a common component of buffers used for nucleic acid extraction .

HY-B0178AR

Guanidine hydrochloride (Standard) Guanidinium chloride (Standard); Aminoformamidine hydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Autophagy Reference Standards Endogenous Metabolite
Guanidine (hydrochloride) (Standard) is the analytical standard of Guanidine (hydrochloride). This product is intended for research and analytical applications. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

HY-N1051

Zarzissine	Alkaloids Animals Other Alkaloids Morus alba L. Plants Moraceae Source Classification	Bacterial
Zarzissine is a cytotoxic guanidine alkaloid that can be isolated from the Mediterranean sponge Anchinoe paupertas. Zarzissine shows antimicrobial and anticancer activities .

Cat. No.	Product Name	Chemical Structure

HY-W105860S

Guanidine-15N3 hydrobromide
Guanidine Hydrobromide- ¹⁵N₃ is the ¹⁵N labeled Guanidine Hydrobromide[1].

HY-B0178AS

Guanidine-13C,15N3 hydrochloride
Guanidine- ¹³C, ¹⁵N₃ (hydrochloride)is the ¹³C-labeled and ¹⁵N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

HY-W710540

Guanidine-15N3 hydrochloride
Guanidine- ¹⁵N₃ hydrochloride is the ¹⁵N-labeled Guanidine Hydrobromide (HY-W710540) .

HY-B0178AS1

Guanidine-d5 hydrochloride
Guanidine-d₅ (hydrochloride) is the deuterium labeled Guanidine hydrochloride . Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins .

HY-W023072S

Agmatine-d8 dihydrochloride
Agmatine-d₈ (dihydrochloride) (1-(4-Aminobutyl)guanidine-d₈ (dihydrochloride)) is the deuterium labeled 1-(4-Aminobutyl)guanidine dihydrochloride (HY-W023072).

HY-W777037

*2,3-Dichlorobenzamidyl Guanidine-13C2*
2,3-Dichlorobenzamidyl Guanidine- ¹³C₂ is the ¹³C-labeled 2-(2,3-Dichlorobenzoyl)hydrazine-1-carboximidamide (HY-W727201).

HY-W699749

Guanyl Urea hydrochloride-15N4
Guanyl Urea hydrochloride- ¹⁵N₄ is the ¹⁵N labeled Carbamoyl-guanidine Amidino Urea (HY-W738276).

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

guanidine

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products