4-Chlorophenylguanidine hydrochloride
Based on 1 Customer Validation
4-Chlorophenylguanidine hydrochloride is an urokinase-type plasminogen activator inhibitor. 4-Chlorophenylguanidine hydrochloride is a potent ASIC3 positive allosteric modulator and reverses the effects of ASIC3 desensitization. 4-Chlorophenylguanidine hydrochloride influences ASIC3 activity through directly activating the channel and increasing proton sensitivity. 4-Chlorophenylguanidine hydrochloride offers a chemical backbone for the design of new ASIC3 ligands to study ASIC3 in vivo.
For research use only. We do not sell to patients.
- Purity: 99.07%
- CAS No.: 14279-91-5
- Formula: C7H9Cl2N3
- Molecular Weight:206.08
-
Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
4-Chlorophenylguanidine hydrochloride influences ASIC3 activity through directly activating the channel and increasing proton sensitivity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 14279-91-5
-
Appearance Solid
-
Molecular Weight 206.08
-
Formula C7H9Cl2N3
-
Color Off-white to gray
-
SMILES
NC(NC1=CC=C(Cl)C=C1)=N.[H]Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 125 mg/mL (606.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (269 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8526 mL | 24.2629 mL | 48.5258 mL | 121.3145 mL |
| 5 mM | 0.9705 mL | 4.8526 mL | 9.7052 mL | 24.2629 mL | |
| 10 mM | 0.4853 mL | 2.4263 mL | 4.8526 mL | 12.1314 mL | |
| 15 mM | 0.3235 mL | 1.6175 mL | 3.2351 mL | 8.0876 mL | |
| 20 mM | 0.2426 mL | 1.2131 mL | 2.4263 mL | 6.0657 mL | |
| 25 mM | 0.1941 mL | 0.9705 mL | 1.9410 mL | 4.8526 mL | |
| 30 mM | 0.1618 mL | 0.8088 mL | 1.6175 mL | 4.0438 mL | |
| 40 mM | 0.1213 mL | 0.6066 mL | 1.2131 mL | 3.0329 mL | |
| 50 mM | 0.0971 mL | 0.4853 mL | 0.9705 mL | 2.4263 mL | |
| 60 mM | 0.0809 mL | 0.4044 mL | 0.8088 mL | 2.0219 mL | |
| 80 mM | 0.0607 mL | 0.3033 mL | 0.6066 mL | 1.5164 mL | |
| 100 mM | 0.0485 mL | 0.2426 mL | 0.4853 mL | 1.2131 mL |