217 Results for "

hepatitis+B

" in MedChemExpress (MCE) Product Catalog:
Products (217)

217 Results for "hepatitis+B" in MCE Product Catalog:

22
22 Publications Verification
Cat. No.: HY-B1192
CAS No.: 50-50-0
Synonyms: β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate
Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice .
loading...
    loading...
19
19 Cited Publications
Cat. No.: HY-B0250
CAS No.: 134678-17-4
Synonyms: BCH-189
Research Areas:  

Infection Cancer

Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS .
loading...
    loading...
17
17 Cited Publications
Cat. No.: HY-N0063
CAS No.: 65995-63-3
Punicalagin is a polyphenol ingredient isolated from Pomegranate (Punica granatum L.) or the leaves of Terminalia catappa L.. Punicalagin is a reversible and non-competitive 3CL pro inhibitor and inhibits SARS-CoV-2 replication in vitro. Punicalagin is an anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects. Punicalagin has the potential for the research of COVID-19 .
loading...
    loading...
14
14 Cited Publications
Cat. No.: HY-100029
CAS No.: 298708-81-3
Purity:  99.24%
Target:  

HBV

Research Areas:  

Infection

BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-13782
CAS No.: 202138-50-9
Purity:  99.67%
Synonyms: Tenofovir DF; Bis(POC)-PMPA fumarate; GS 4331 fumarate
Research Areas:  

Infection

Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-13782A
CAS No.: 201341-05-1
Purity:  99.52%
Synonyms: Bis(POC)-PMPA; GS 4331
Research Areas:  

Cancer

Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-N0058
CAS No.: 57378-72-0
Synonyms: Isochlorogenic acid C; 4,5-diCQA
4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) is an antioxidant, can be isolated from Gynura divaricata and Laggera alata. 4,5-Dicaffeoylquinic acid reduces islet cell apoptosis and improves pancreatic function in type 2 diabetic mice, and has obvious inhibitory activities against yeast α-glucosidase. 4,5-Dicaffeoylquinic acid inhibits prostate cancer cells through cell cycle arrest. 4,5-Dicaffeoylquinic acid also has anti-apoptotic, anti-injury and anti-hepatitis B virus effects .
loading...
    loading...
10
10 Cited Publications
Cat. No.: HY-13910
CAS No.: 147127-20-6
Purity:  99.92%
Synonyms: GS 1278; PMPA
Tenofovir (GS 1278; PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV) .
loading...
    loading...
10
10 Cited Publications
Cat. No.: HY-13910A
CAS No.: 206184-49-8
Purity:  ≥98.0%
Synonyms: GS 1278 hydrate; PMPA hydrate
Tenofovir hydrate (GS 1278 hydrate; PMPA hydrate) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV) .
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-N6666
CAS No.: 24356-66-9
Vidarabine monohydrate is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine monohydrate competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine monohydrate inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine monohydrate is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine monohydrate can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-B0277
CAS No.: 5536-17-4
Synonyms: Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine
Vidarabine (Ara-A) is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-N0853
CAS No.: 19885-10-0
Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N0699
CAS No.: 2034-69-7
Synonyms: Dephnoretin; Thymelol
Daphnoretin (Dephnoretin; Thymelol) is a protein kinase C (PKC) activator that inhibits the expression of hepatitis B virus (HBV) surface antigen (HBsAg) and exhibits antiviral activity. Daphnoretin exerts its antitumor effects by inhibiting the activation of the PI3K/AKT signaling pathway and triggers the mitochondrial apoptosis pathway. Daphnoretin alleviates chondrocyte apoptosis and inflammatory responses by inhibiting endoplasmic reticulum stress and activation of the NLRP3 inflammasome. Daphnoretin regulates the differentiation and maturation of dendritic cells, inhibits their immunostimulatory function by downregulating the phosphorylation level of JNK, and thus exerts a protective effect in skin graft rejection .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-N0639
CAS No.: 65995-64-4
Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV). Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-109137
CAS No.: 2004677-13-6
Purity:  98.18%
Synonyms: GS-9688
Research Areas:  

Infection

Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-112564
CAS No.: 1572510-42-9
Purity:  99.94%
Target:  

HBV

Research Areas:  

Infection

JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM).
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-100029A
CAS No.: 298708-79-9
Purity:  98.92%
Target:  

HBV

Research Areas:  

Infection

BAY 41-4109 racemate is the racemate of BAY 41-4109. BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-109168
CAS No.: 1638266-40-6
Purity:  99.24%
Synonyms: JNJ-6379; JNJ-56136379
Target:  

HBV DNA/RNA Synthesis

Research Areas:  

Infection

Bersacapavir (JNJ-6379) is an HBV capsid assembly modulator. Bersacapavir exerts a dual mechanism of action against both early and late stages of HBV infection by forming complete genome-free empty capsids and inhibiting de novo synthesis of cccDNA. Bersacapavir inhibits HBV replication. Bersacapavir can be used in the research of hepatitis B .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-109195
CAS No.: 2090064-66-5
Purity:  99.73%
Synonyms: ABI-H0731
Target:  

HBV

Research Areas:  

Infection Inflammation/Immunology

Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir (ABI-H0731) suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s from 1.84 μM to 7.3 μM .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-100028
CAS No.: 211364-06-6
Purity:  98.39%
Target:  

HBV DNA/RNA Synthesis

Research Areas:  

Infection Cancer

AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells .
loading...
    loading...