2004677-13-6
2004677-13-6
Chemical Structure
Selgantolimod
Synonym(s): GS-9688
- CAS. Nr.: 2004677-13-6
- Formula:C14H20FN5O
- Molecular Weight:293.34
IUPAC Name: (R)-2-((2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino)-2-methylhexan-1-ol
InChIKey: HTCJUBZBSJQWBW-CQSZACIVSA-N
SMILES: C[C@@](CCCC)(CO)NC1=NC(N)=NC2=C1N=CC(F)=C2
Biological Activity: Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Selgantolimod | 98.18% | Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection. | ||||||||||||||||||||
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Selgantolimod (Standard) | ≥98% | Selgantolimod (Standard) is the analytical standard of Selgantolimod (HY-109137). This product is intended for research and analytical applications. Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection. | ||||||||||||||||||||
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References
- [1]. Jules Levin. Efficacy and Safety of Oral TLR8 Agonist Selgantolimod in Virally Suppressed Adult Patients With Chronic Hepatitis B: a Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. 2019 Nov 8-12.
- [2]. Benjamin Ryan. Selgantolimod Shows Promise as Treatment for Hepatitis B. November 18, 2019.
- [3]. Romas Geleziunas, et al. Modulators of toll-like receptors for the treatment of hiv. US20170071944A1.
