7 Results for "

human carboxylesterase 1

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "human carboxylesterase 1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-106409
CAS No.: 914382-60-8
Purity:  99.65%
Synonyms: CHR-2845
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias .
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Cat. No.: HY-N1377
CAS No.: 10176-66-6
Synonyms: Lysionotin
Nevadensin (Lysionotin), a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells. Nevadensin has a variety of pharmacological effects such as anti-inflammatory, anti-tumour, anti-hypertensive, anti-tubercular, antitussive, antioxidant and anti-microbial activities .
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Cat. No.: HY-144809
CAS No.: 194235-21-7
Purity:  99.92%
Research Areas:  

Metabolic Disease

Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of pancreatic lipase (PL) and human carboxylesterase 1A (hCES1A) with IC50 values of 2.13 µM and 0.055  µM against PL and hCES1A .
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Cat. No.: HY-P7730
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES1; Cocaine carboxylesterase; carboxylesterase 1; Retinyl Ester Hydrolase; HMSE; Serine Esterase 1; CES2; CES1A1; SES1; CES1A2; CEH; Egasyn; HMSE1; HCE-1; carboxylesterase 1 (Monocyte/Macrophage Serine Esterase 1); ACAT; human Monocyte/Macrophage Serine
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P703886
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CES1; Cocaine carboxylesterase; carboxylesterase 1; Retinyl Ester Hydrolase; HMSE; Serine Esterase 1; CES2; CES1A1; SES1; CES1A2; CEH; Egasyn; HMSE1; HCE-1; carboxylesterase 1 (Monocyte/Macrophage Serine Esterase 1); ACAT; human Monocyte/Macrophage Serine
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-106409R
CAS No.: 914382-60-8
Synonyms: CHR-2845 (Standard)
Research Areas:  

Cancer

Tefinostat (Standard) is the analytical standard of Tefinostat (HY-106409). This product is intended for research and analytical applications. Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias .
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Cat. No.: HY-N1377R
CAS No.: 10176-66-6
Synonyms: Lysionotin (Standard)
Nevadensin (Standard) (Lysionotin (Standard)) is the analytical standard of Nevadensin (HY-N1377). This product is intended for research and analytical applications. Nevadensin, a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells. Nevadensin has a variety of pharmacological effects such as anti-inflammatory, anti-tumour, anti-hypertensive, anti-tubercular, antitussive, antioxidant and anti-microbial activities.
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