914382-60-8
914382-60-8
Chemical Structure
Tefinostat
Synonym(s): CHR-2845
- CAS No.: 914382-60-8
- Formula:C28H37N3O5
- Molecular Weight:495.61
IUPAC Name: cyclopentyl (S)-2-((4-(8-(hydroxyamino)-8-oxooctanamido)benzyl)amino)-2-phenylacetate
InChIKey: GLNWREBYRLDPQP-MHZLTWQESA-N
SMILES: O=C(OC1CCCC1)[C@H](C2=CC=CC=C2)NCC3=CC=C(NC(CCCCCCC(NO)=O)=O)C=C3
Biological Activity: Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Tefinostat | 99.65% | Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias. | ||||||||||||||||||||
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Tefinostat (Standard) | ≥98% | Tefinostat (Standard) is the analytical standard of Tefinostat (HY-106409). This product is intended for research and analytical applications. Tefinostat (CHR-2845) is a monocyte/macrophage targeted histone deacetylase (HDAC) inhibitor. Tefinostat can be cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Tefinostat can be used for the research of leukaemias. | ||||||||||||||||||||
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