3 Results for "

human iPSC-derived microglia

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "human iPSC-derived microglia" in MCE Product Catalog:

Cat. No.: HY-160842
CAS No.: 3024322-57-1
Target:  

c-Fms

Research Areas:  

Neurological Disease

CSF1R-IN-24 (Example 134) is an orally active CSF1R inhibitor. CSF1R-IN-24 significantly inhibits the survival of human ipSC-derived microglia (hiPSC-MG) .
loading...
    loading...
Cat. No.: HY-184157
IB15C is an ILT3 (LILRB4) inhibitor with a human Kd of 0.92 μM. IB15C binds to a specific ILT3 pocket, disrupts ApoE interaction, and interferes with downstream inhibitory signaling pathways. IB15C reduces SHP1 and SHP2 phosphorylation, suppresses pro-inflammatory cytokine secretion, enhances amyloid uptake, and attenuates NF-κB activation. IB15C can be used for the research of alzheimer's disease .
loading...
    loading...
Cat. No.: HY-116705G
CAS No.: 70763-62-1
Synonyms: 2-Fluorofucose (GMP)
2-Deoxy-2-fluoro-L-fucose (2-Fluorofucose) GMP is a fucosyltransferase inhibitor that inhibits core fucosylation modification in cells. 2-Deoxy-2-fluoro-L-fucose GMP promotes the production of defucosylated IgG1 antibodies in IgG1-expressing cell culture systems; it regulates the levels of inflammatory cytokines such as IL-1β, IL-6 and TGF-β in human induced pluripotent stem cell-derived microglia. 2-Deoxy-2-fluoro-L-fucose GMP can be used in the research of related diseases including dengue fever and Alzheimer's disease .
loading...
    loading...