2 Results for "

human platelet DP receptors

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "human platelet DP receptors" in MCE Product Catalog:

Cat. No.: HY-137308
CAS No.: 59894-05-2
Purity:  ≥99.0%
Synonyms: 15R-PGD2
Research Areas:  

Inflammation/Immunology

15(R)-Prostaglandin D2 is a potential prostatic hormone DP(2) receptor (Prostaglandin Receptor) agonist with anti-inflammatory activity. 15(R)-Prostaglandin D2 increases actin polymerization in human eosinophils and increases cAMP levels in platelets .
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Cat. No.: HY-182473
CAS No.: 170552-18-8
Research Areas:  

Neurological Disease

AL-6556 is a full agonist of the DP receptor and a partial agonist of the EP2 receptor. AL-6556 has an EC50 of 799 nM for bovine DP, a Ki of 3200 nM for human DP, and an EC50 of 1180 nM for human EP2, with selectivity over EP3, FP, IP, TP and 19 non-prostaglandin receptors. AL-6556 stimulates cAMP production via receptor activation and reduces intraocular pressure through aqueous humor inflow and outflow mechanisms. AL-6556 can be used in research related to ocular hypertension and glaucoma .
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