294 Results for "

human serum

" in MedChemExpress (MCE) Product Catalog:
Products (294)

294 Results for "human serum" in MCE Product Catalog:

  • Targets Recommended:
9
9 Publications Verification
Cat. No.: HY-13402
CAS No.: 172732-68-2
Purity:  99.23%
Synonyms: LY315920
Target:  

Phospholipase

Research Areas:  

Inflammation/Immunology

Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .
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9
9 Publications Verification
Cat. No.: HY-13402A
CAS No.: 172733-42-5
Purity:  ≥98.0%
Synonyms: LY315920 sodium
Target:  

Phospholipase

Research Areas:  

Inflammation/Immunology

Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively .
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5
5 Cited Publications
Cat. No.: HY-P1956
CAS No.: 70024-90-7
Synonyms: human serum albumin
HSA Protein (Human serum albumin) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ?) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant HSA Protein expressed in a microbial expression system.
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3
3 Cited Publications
Cat. No.: HY-18780
CAS No.: 1351758-37-6
Target:  

Pantetheinase

Research Areas:  

Cancer

RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively .
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2
2 Cited Publications
Cat. No.: HY-N6678
CAS No.: 5975-78-0
Zearalanone is a reductive metabolite of Zearalenone (HY-103447). Zearalanone binds to serum albumin across multiple species. Zearalanone enhances the binding affinity of Warfarin (HY-B0687) to serum albumin .
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2
2 Cited Publications
Cat. No.: HY-P70485
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: Vitronectin; VN; S-Protein; serum-Spreading Factor; V75; VTN
Species:  
Source:  
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2
2 Cited Publications
Cat. No.: HY-P71067
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: serum Amyloid P-Component; SAP; 9.5S Alpha-1-Glycoprotein; APCS; PTX2
Species:  
Source:  
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2
2 Cited Publications
Cat. No.: HY-22024
CAS No.: 491-78-1
Synonyms: 5-OH-Flavone
5-Hydroxyflavone (5-OH-Flavone) is a flavonoid compound that undergoes oxidation-mediated conversion to 5,7-dihydroxyflavone and 5,6,7-trihydroxyflavone by human cytochrome P450 enzymes .
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1
1 Cited Publications
Cat. No.: HY-P1956A
CAS No.: 70024-90-7
Synonyms: human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) (Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO ?) in the vascular wall, contributing to the reduction of blood pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can be used for in vitro cell culture .
This product is human serum albumin recombinantly expressed in an Escherichia coli expression system.
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1
1 Cited Publications
Cat. No.: HY-16710
CAS No.: 65096-46-0
Synonyms: GPN; Glycylproline p-nitroanilide tosylate
GPDA (GPN; Glycylproline p-nitroanilide tosylate) is a chromogenic substrate of prolyl dipeptidyl aminopeptidase. GPDA is used to detect the activity of prolyl dipeptidyl aminopeptidase in human serum .
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1
1 Cited Publications
Cat. No.: HY-W007894
CAS No.: 595-46-0
Dimethylmalonic acid is a short-chain dicarboxylic acid in human serum. Dimethylmalonic acid is also a volatile organic compound detected in alveolar breath .
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1
1 Cited Publications
Cat. No.: HY-P71277
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: serum Amyloid A-4 Protein; Constitutively Expressed serum Amyloid A Protein; C-SAA; SAA4; CSAA
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P78393
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Albumin; ALB; serum albumin; ANALBA; FDAH; PRO0883; PRO0903; PRO1341
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P70510
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: serum Amyloid A-1 Protein; SAA; SAA1
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-K6014

MCE Organoid Cryopreservation Medium (Serum Free) is a ready-to-use cryopreservation medium, widely applicable to organoids and cell lines derived from various mammals (such as human, mouse, pig, cow, etc.). The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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1
1 Cited Publications
Cat. No.: HY-NP199
Bovine pituitary extract is a bovine pituitary extract that can be used as a mitogenic supplement in serum-free growth media. Bovine pituitary extract is rich in growth factors. Bovine pituitary extract not only promotes the proliferation of corneal keratinocytes and maintains their phenotype, but also exerts significant antioxidant stress protective effects on human prostate epithelial cells .
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1
1 Cited Publications
Cat. No.: HY-113509
CAS No.: 89663-86-5
Purity:  98.0%
Synonyms: LXA4
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties . Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways . Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM .
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1
1 Cited Publications
Cat. No.: HY-15790
CAS No.: 439087-18-0
Purity:  99.91%
Synonyms: A 3309; AZD 7806
Elobixibat (A 3309; AZD 7806) is an orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to study metabolic syndrome. Elobixibat can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly .
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1
1 Cited Publications
Cat. No.: HY-15790A
CAS No.: 1633824-78-8
Purity:  99.44%
Synonyms: A 3309 hydrate; AZD 7806 hydrate
Elobixibat (A 3309; AZD 7806) hydrate is an orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat hydrate can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to study metabolic syndrome. Elobixibat hydrate can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly .
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1
1 Cited Publications
Cat. No.: HY-128342
CAS No.: 2365402-67-9
Purity:  99.14%
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Compound C5-IN-1 (Compound 7) is a selective allosteric inhibitor of complement component protein C5. Compound C5-IN-1 prevents C5 from being cleaved by C5 convertase, inhibits the cleavage of C5 into C5a and C5b, and thus blocks the formation of membrane attack complex (MAC). Compound C5-IN-1 has an IC50 of 0.77 μM and 5 nM in 50% human whole blood and 2% human serum to block MAC deposition induced by zymosan, respectively. Compound C5-IN-1 can be used to study diseases related to complement overactivation, such as paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS) .
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