491-78-1
491-78-1
Chemical Structure
5-Hydroxyflavone
Synonym(s): 5-OH-Flavone
- CAS No.: 491-78-1
- Formula:C15H10O3
- Molecular Weight:238.24
IUPAC Name: 5-hydroxy-2-phenyl-4H-chromen-4-one
InChIKey: IYBLVRRCNVHZQJ-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=CC=C2)OC3=CC=CC(O)=C13
Biological Activity: 5-Hydroxyflavone (5-OH-Flavone) is a flavonoid compound that undergoes oxidation-mediated conversion to 5,7-dihydroxyflavone and 5,6,7-trihydroxyflavone by human cytochrome P450 enzymes[1][2].
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5-Hydroxyflavone | 99.83% | 5-Hydroxyflavone (5-OH-Flavone) is a flavonoid compound that undergoes oxidation-mediated conversion to 5,7-dihydroxyflavone and 5,6,7-trihydroxyflavone by human cytochrome P450 enzymes. | ||||||||||||||||||||
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References
- [1]. Nagayoshi H, et al. Oxidation of Flavone, 5-Hydroxyflavone, and 5,7-Dihydroxyflavone to Mono-, Di-, and Tri-Hydroxyflavones by Human Cytochrome P450 Enzymes. Chem Res Toxicol. 2019;32(6):1268-1280. [Content Brief]
- [2]. Shia CS, et al. Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites. J Agric Food Chem. 2009;57(1):83-89. [Content Brief]
Keywords
