5-Methoxyflavone (Standard)
5-Methoxyflavone (Standard) is the analytical standard of 5-Methoxyflavone (HY-107790). This product is intended for research and analytical applications. 5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 42079-78-7
- 화학식: C16H12O3
- 분자량:252.26
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
DNA polymerase-beta[1].
Chemical Information
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CAS No. 42079-78-7
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분자량 252.26
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화학식 C16H12O3
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SMILES
O=C1C=C(C2=CC=CC=C2)OC3=CC=CC(OC)=C13
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Merlo S, et al. Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity. J Nat Prod. 2015 Nov 25;78(11):2704-11. [Content Brief]
[2]. Shanmugasundaram J, et al. Sedative-hypnotic like effect of 5-methoxyflavone in mice and investigation on possible mechanisms by in vivo and in silico methods. Biomed Pharmacother. 2018 Dec;108:85-94. [Content Brief]
[3]. Wudtiwai B, et al. Methoxyflavone derivatives modulate the effect of TRAIL-induced apoptosis in human leukemic cell lines. J Hematol Oncol. 2011 Dec 21;4:52. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)