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Cat. No.: HY-107790R

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5-Methoxyflavone (Standard)

5-Methoxyflavone (Standard) is the analytical standard of 5-Methoxyflavone (HY-107790). This product is intended for research and analytical applications. 5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors.

For research use only. We do not sell to patients.

CAS No.: 42079-78-7
Formula: C₁₆H₁₂O₃
Molecular Weight:252.26

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

5-Methoxyflavone (Standard) Chemical Structure

CAS No.: 42079-78-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
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Biological Activity

Description

IC₅₀ & Target

DNA polymerase-beta^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 42079-78-7
Molecular Weight 252.26
Formula C₁₆H₁₂O₃
SMILES

O=C1C=C(C2=CC=CC=C2)OC3=CC=CC(OC)=C13
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Merlo S, et al. Identification of 5-Methoxyflavone as a Novel DNA Polymerase-Beta Inhibitor and Neuroprotective Agent against Beta-Amyloid Toxicity. J Nat Prod. 2015 Nov 25;78(11):2704-11. [Content Brief]

[2]. Shanmugasundaram J, et al. Sedative-hypnotic like effect of 5-methoxyflavone in mice and investigation on possible mechanisms by in vivo and in silico methods. Biomed Pharmacother. 2018 Dec;108:85-94. [Content Brief]

[3]. Wudtiwai B, et al. Methoxyflavone derivatives modulate the effect of TRAIL-induced apoptosis in human leukemic cell lines. J Hematol Oncol. 2011 Dec 21;4:52. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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5-Methoxyflavone (Standard)

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

5-Methoxyflavone (Standard) Related Classifications

HY-107790R Related Classifications