Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
human thymidine kinase
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "human thymidine kinase" in MCE Product Catalog:
Cat. No.: HY-W342664
CAS No.: 55612-21-0
Synonyms: FIRU
Target:
Research Areas:
2'-Deoxy-2'-fluoro-5-iodouridine (FIRU) is a nucleoside analog. When labeled with 123I, 2'-Deoxy-2'-fluoro-5-iodouridine accumulates highly selectively in tumors expressing the HSV1-tk gene. Radiolabeled 2'-Deoxy-2'-fluoro-5-iodouridine enables imaging of adenovirus-mediated HSV1-tk suicide gene transfer .
Cat. No.: HY-50735
CAS No.: 69123-90-6
Synonyms: NSC 382097; FIAC; FOAC
Target:
Research Areas:
Fiacitabine (NSC 382097; FIAC; FOAC) is a potent and highly selective anti-herpesvirus agent. Fiacitabine acts as an inhibitor of HSV DNA polymerase, with a Ki of 0.26 μM for HSV-1 and 0.42 μM for HSV-2, respectively. Fiacitabine can be efficiently phosphorylated by thymidine kinase encoded by the virus itself to generate FIACTP, an active triphosphate metabolite. Fiacitabine is applicable to research related to herpesvirus infections .
Cat. No.: HY-114247
CAS No.: 69256-17-3
Synonyms: D-FMAU
Target:
FMAU is a nucleoside analog and cell proliferation marker that can be phosphorylated by human thymidine kinase and subsequently incorporated into DNA. FMAU is applicable to research related to herpes simplex virus infection, various cancers, hepatitis B virus infection, and Epstein-Barr virus infection .
Cat. No.: HY-188062
CAS No.: 138751-31-2
2-Fluoroneplanocin A is an Antiviral agent. 2-Fluoroneplanocin A inhibits rabbit Adenosylhomocysteine hydrolase with an IC50 of 0.20 μg/mL. 2-Fluoroneplanocin A exhibits antiviral activity against vaccinia virus, vesicular stomatitis virus, parainfluenza virus, reovirus, Junín virus, Tacaribe virus, cytomegalovirus, measles virus, mumps virus, and thymidine kinase-deficient varicella-zoster virus; it shows no antiviral activity against herpes simplex virus, coxsackievirus B4, poliovirus type 1, Semliki Forest virus, or HIV at subtoxic concentrations. 2-Fluoroneplanocin A can be used in research related to vaccinia virus infection, vesicular stomatitis virus infection, parainfluenza virus infection, reovirus infection, Junín virus infection, Tacaribe virus infection, human cytomegalovirus infection, measles virus infection, mumps virus infection, and varicella-zoster virus infection .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
