69256-17-3
Chemical Structure
FMAU
Synonym(s): D-FMAU
- CAS No.: 69256-17-3
- Formula:C10H13FN2O5
- Molecular Weight:260.22
IUPAC Name: 1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: GBBJCSTXCAQSSJ-JVZYCSMKSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N(C(N2)=O)C=C(C)C2=O)O[C@@H]1CO
Biological Activity: FMAU is a nucleoside analog and cell proliferation marker that can be phosphorylated by human thymidine kinase and subsequently incorporated into DNA. FMAU is applicable to research related to herpes simplex virus infection, various cancers, hepatitis B virus infection, and Epstein-Barr virus infection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FMAU | 99.04% | FMAU is a nucleoside analog and cell proliferation marker that can be phosphorylated by human thymidine kinase and subsequently incorporated into DNA. FMAU is applicable to research related to herpes simplex virus infection, various cancers, hepatitis B virus infection, and Epstein-Barr virus infection. | ||||||||||||||||||||
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- [1]. Alauddin MM. Journey of 2'-deoxy-2'-fluoro-5-methyl-1-β-D-arabinofuranosyluracil (FMAU): from Antiviral Drug to PET Imaging Agent. Curr Med Chem. 2018;25(16):1867-1878. [Content Brief]
- [2]. Nam Hyun Jo, et al. Synthesis and Evaluation of F-18 Labeled 2'-Deoxy-2'-fluoro-5-methyl-1-β-L-arabinofuranosyluracil (L-[18F]FMAU. Bull. Korean Chem. Soc. 2007, Vol. 28.
Keywords
