85 Results for "

human urine

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "human urine" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-153169
CAS No.: 2754428-18-5
Purity:  99.30%
Synonyms: 6PPD-Quinone
6PPD-Q (6PPD-Quinone) is an environmental pollutant that can be detected in human urine and is widely present in the environment. 6PPD-Q targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 exhibiting the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q induces intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. 6PPD-Q is applicable in research on environmental toxicology, neurodegenerative diseases, and inflammation-related disorders .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-P72974
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DNASE1; DRNI; Prev. DNL1; Alternative Protein DNASE1; Deoxyribonuclease I; DNase I, Lysosomal; Deoxyribonuclease-1; DNase I; Dornase Alfa; DNAse1; Deoxyribonuclease 1; human urine Deoxyribonuclease I
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W002105
CAS No.: 3238-40-2
2,5-Furandicarboxylic acid is an endogenous metabolite that can be detected in human urine. 2,5-Furandicarboxylic acid serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters. 2,5-Furandicarboxylic acid can be used as the raw material for various chemical intermediates to synthesize polymers, polyurethanes, thermosetting resins, and plasticizers .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N6678
CAS No.: 5975-78-0
Zearalanone is a reductive metabolite of Zearalenone (HY-103447). Zearalanone binds to serum albumin across multiple species. Zearalanone enhances the binding affinity of Warfarin (HY-B0687) to serum albumin .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P0063
CAS No.: 89030-95-5
Synonyms: GHK-Cu
Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N9457
CAS No.: 60696-62-0
Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W010981
CAS No.: 77-90-7
Synonyms: Tributyl O-acetylcitrate; ATBC
Acetyl tributyl citrate (Tributyl O-acetylcitrate) is a pharmaceutical excipient and biodegradable hydrophobic plasticizer. Acetyl tributyl citrate can be used in cosmetics, food packaging, and as a flavoring substance for food .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-113095
CAS No.: 178167-75-4
Purity:  98.30%
γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-128129
CAS No.: 892742-76-6
Purity:  99.68%
Target:  

Urea Transporter

Research Areas:  

Metabolic Disease

UT-B-IN-1 (UTBINH-14) is a reversible, competitive and selective urea transporter-B (UT-B) inhibitor with IC50 values of 10 and 25 nM for human and mouse UT-B, respectively. UT-B-IN-1 shows low toxicity and high selectivity for UT-B over UT-A isoforms. UT-B-IN-1 increases urine output and reduces urine osmolality of mice. UT-B-IN-1 can be used for diuretic mechanism research .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P2281A
Synonyms: Atrial natriuretic peptide (1-28) TFA
Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) TFA inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) TFA increases cGMP levels in RMIC cells with an IC50 of 1.2 nM .
loading...
    loading...
Cat. No.: HY-113114
CAS No.: 53-05-4
Purity:  99.96%
Tetrahydrocortisone is a corticosteroid catalyzed from endogenous glucocorticoids by AKR1D1 (5β-reductase). Its formation is mediated by AKR1D1 and regulated by the glucocorticoid receptor (GR). As one of the final products of glucocorticoid inactivation metabolism, Tetrahydrocortisone participates in the maintenance of glucocorticoid metabolic homeostasis in vivo. Tetrahydrocortisone can be used for mechanistic studies of metabolic diseases such as non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes, and also serves as a biomarker for in vivo AKR1D1 activity and glucocorticoid metabolic status .
loading...
    loading...
Cat. No.: HY-77641
CAS No.: 16534-24-0
Cinnamoylglycine is a human urinary metabolite and PPG analog. Cinnamoylglycine is a conjugate of cinnamic acid and glycine. Cinnamoylglycine is used as a urine marker. Cinnamoylglycine can be used in adipogenic differentiation studies .
loading...
    loading...
Cat. No.: HY-N13356
CAS No.: 5652-48-2
Synonyms: gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr
L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .
loading...
    loading...
Cat. No.: HY-129912
CAS No.: 82414-35-5
Purity:  99.96%
N1,N8-Diacetylspermidine is a diacetylated polyamine metabolite and also a urine biomarker associated with diagnosis, prognosis and disease severity. Urinary levels of N1,N8-Diacetylspermidine increase in breast cancer, colorectal cancer, urogenital malignancies and Parkinson's disease. N1,N8-Diacetylspermidine can be used in studies related to breast cancer, colorectal cancer, urogenital malignancies and Parkinson's disease .
loading...
    loading...
Cat. No.: HY-113247
CAS No.: 3588-17-8
Purity:  99.93%
trans-trans-Muconic acid is a urinary metabolite of Benzene. trans-trans-Muconic acid serves as a urinary biomarker for occupational benzene exposure .
loading...
    loading...
Cat. No.: HY-43470
CAS No.: 570-62-7
3α,12β-Dihydroxycholanoic acid is a bile acid that can be isolated from urine specimens of healthy humans .
loading...
    loading...
Cat. No.: HY-165151
CAS No.: 28925-89-5
Synonyms: Urochrome hydrochloride
Target:  

Endogenous Metabolite

Research Areas:  

Others

Urobilin hydrochloride is the metabolite of Hemoglobin (HY-P2995), that can be excreted through urine and feces in many mammals. Urobilin hydrochloride can be used as an indicator of human waste pollution .
loading...
    loading...
Cat. No.: HY-131516
CAS No.: 77591-18-5
Purity:  96.8%
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

Tiopronin-cysteine disulfide is a soluble disulfide metabolite/derivative of Tiopronin (HY-B0373) formed by reaction of Tiopronin with cystine. Tiopronin-cysteine disulfide reduces cystine crystal formation in cystinuria. Tiopronin-cysteine disulfide can be used for the research of cystinuria .
loading...
    loading...
Cat. No.: HY-D0862
CAS No.: 145551-16-2
DIDNTB is a dye. DIDNTB exhibits chemical sensitivity and specificity toward albumin. DIDNTB is much less affected by other proteins. DIDNTB enables the detection of urinary albumin at concentrations ≥10 mg/L .\n
loading...
    loading...
Cat. No.: HY-W042214
CAS No.: 19395-41-6
Synonyms: Ritalinate
Ritalinic acid (Ritalinate) is a metabolite of Methylphenidate. Ritalinic acid has no biological activity or only extremely low biological activity. The concentration of Ritalinic acid detected in university campus sewage shows a gradual upward trend in the first semester, while no obvious periodic variation pattern related to academic stress is observed in the second semester. Ritalinic acid can be used in studies related to attention deficit disorder, narcolepsy, depression and attention deficit hyperactivity disorder .
loading...
    loading...