Search Result

Results for "

immunoglobulin G1-kappa

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Antibody (1) ANGPTL (1) c-Kit (1) CCR (1) CD276/B7-H3 (1) CD28 (1) CD3 (1) Claudin (1) CTLA-4 (3) EGFR (1) GLP Receptor (1) IFNAR (1) IGF-1R (1) NTPDase (1) PD-1/PD-L1 (1) Transmembrane Glycoprotein (1) Virus Protease (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (12) Endocrinology (1) Infection (1) Inflammation/Immunology (9) Metabolic Disease (2)

Inhibitors & Agonists

Inhibitory Antibodies

Targets Recommended: Human leukocyte immunoglobulin (Ig)-like receptors (LILR) LILRB Tim3

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-P99367

Ifinatamab DS-7300a Antibody; MABX-9001A Antibody	CD276/B7-H3	Inflammation/Immunology Cancer
Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur .

HY-P990047

Maridebart AMG133 antibody	ADC Antibody GLP Receptor	Metabolic Disease
Maridebart (AMG133 antibody) is a human immunoglobulin G1-kappa, anti-GIPR (gastric inhibitory polypeptide receptor) monoclonal antibody. Maridebart is the antibody portion of Maridebart cafraglutide (HY-164535) and can be used for the synthesis of antibody-drug conjugates (ADC). Maridebart can be used for the reserrch of obesity and type 2 diabetes .

HY-P99521

Vibecotamab XmAb14045	CD3	Inflammation/Immunology Cancer
Vibecotamab (XmAb14045) is a potent bispecific antibody targeting both CD123 and CD3. Vibecotamab targets T cell-mediated killing of CD123-expressing cells, regardless of T cell antigen specificity. Vibecotamab is a full length immunoglobulin molecule. Vibecotamab can be studied in research for diseases such as Myelodysplastic syndrome and acute myeloid leukemia. Recommend Isotype Control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3 .

HY-P990045

Lixudebart ALE.F02	Claudin	Endocrinology
Lixudebart (ALE.F02) is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody. Lixudebart disrupts CLDN1 interactions with CD44 and MMP14, reduces renal macrophage infiltration, epithelial activation, and urinary albumin-to-creatinine ratio, and attenuates glomerulosclerosis. Lixudebart can be used for the research of focal segmental glomerulosclerosis .

HY-P990032

Belrestotug EOS-448; EOS884448; GSK4428859A	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Belrestotug (EOS-448) is an antagonistic anti-TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity. Belrestotug can be used for cancer and immunological research such as colon cancer .

HY-P990048

Muzastotug ADG126	CTLA-4	Cancer
Muzastotug is a humanized immunoglobulin G1-kappa, anti-CTLA4 monoclonal antibody. Muzastotug is an immunostimulant and antineoplastic .

HY-P99698

Lesabelimab LDP	PD-1/PD-L1	Inflammation/Immunology Cancer
Lesabelimab (LDP) is an immunoglobulin G1-kappa anti-CD274 monoclonal antibody. CD274 is an immune checkpoint ligand, represses antitumour immunity through the interaction with PDCD1 receptor .

HY-P990079

Renvistobart BMS-986207; ONO-4686	CD28	Inflammation/Immunology
Renvistobart is an immunoglobulin G1-κ, anti-[Homo sapiens TIGIT (T cell immunoreceptor with Ig domain and ITIM, VSIG9, VSTM3)] Homo sapiens monoclonal antibody .

HY-P990020

Eglatoprutug FSI-174	c-Kit	Others
Eglatoprutug is an humanized immunoglobulin *G1-kappa, anti-c-Kit* monoclonal antibody .

HY-147407

Imbotolimod	EGFR	Cancer
Imbotolimod, immunoglobulin G1-kappa, is a humanized monoclonal antibody with anti-ERBB2 and antineoplastic activity. Imbotolimod is a derivative of telratolimod .

HY-P990080

Sovipostobart BMS-986249	CTLA-4	Cancer
Sovipostobart is an immunoglobulin G1-kappa, anti-CTLA-4 human monoclonal antibody with cleavable prodomain. Sovipostobart is an immunostimulant and antineoplastic .

HY-P991135

Enzelkitug RO-7502175; RG-6411	CCR	Cancer
Enzelkitug is a humanized immunoglobulin G1-κ monoclonal antibody targeting the human C-C motif chemokine receptor 8 (CCR8). Enzelkitug is promising for research of various solid tumors and hematological malignancies .

HY-P991153

Potravitug	Virus Protease	Infection
Potravitug is a humanized immunoglobulin G1-κ monoclonal antibody targeting the major capsid protein VP1 of BK polyomavirus (BKV). Potravitug is promising for research of BKV-infection-related diseases, such as BKV-induced nephropathy after organ transplantation .

HY-P991134

Elegrobart	IGF-1R	Inflammation/Immunology
Elegrobart is an immunoglobulin G1-κ monoclonal antibody targeting the human insulin-like growth factor 1 receptor (IGF1R). Elegrobart is promising for research of diseases associated with abnormal IGF1R signaling, especially thyroid eye disease .

HY-P992099

Afivastobart AB598	NTPDase	Cancer
Afivastobart (AB598) is a human ENTPD1 (CD39)-targeting monoclonal antibody with antineoplastic activity.Afivastobart binds as a monoclonal antibody to modulate Homo sapiens ENTPD1 activity.Afivastobart constitutes a glycoform alfa immunoglobulin G1-kappa monoclonal antibody .

HY-P991139

Futermestotug	CTLA-4	Cancer
Futermestotug is a humanized immunoglobulin G1-κ monoclonal antibody targeting human cytotoxic T-lymphocyte associated protein 4 (CTLA4). Futermestotug is promising for research of various malignant tumors .

HY-P992105

Corveldebart	ANGPTL	Inflammation/Immunology
Corveldebart is a monoclonal antibody of immunoglobulin G1-kappa that targets ANGPTL4. Corveldebart can be used as an immunomodulator .

HY-P992394

JNJ-55920839 CNTO-6358	IFNAR	Inflammation/Immunology
JNJ-55920839 (CNTO-6358) is a fully human immunoglobulin G1κ monoclonal antibody and a selective Interferon α/ω neutralizer, with a K_d value of 0.9-10.7 pM against hIFNα and a K_d of 1.44 pM against IFNω. JNJ-55920839 can be used in research related to systemic lupus erythematosus .

HY-P992113

Evabosmig	β-catenin Wnt	Metabolic Disease
Evabosmig is a multispecific antibody targeting SOST, DKK-1 and ALB. Evabosmig can be used for the study of osteoporosis .

Cat. No.	상품명	Target	Research Area	Image

HY-P99367

Ifinatamab DS-7300a Antibody; MABX-9001A Antibody	CD276/B7-H3	Inflammation/Immunology Cancer
Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur .

HY-P990047

Maridebart AMG133 antibody	ADC Antibody GLP Receptor	Metabolic Disease
Maridebart (AMG133 antibody) is a human immunoglobulin G1-kappa, anti-GIPR (gastric inhibitory polypeptide receptor) monoclonal antibody. Maridebart is the antibody portion of Maridebart cafraglutide (HY-164535) and can be used for the synthesis of antibody-drug conjugates (ADC). Maridebart can be used for the reserrch of obesity and type 2 diabetes .

HY-P99521

Vibecotamab XmAb14045	CD3	Inflammation/Immunology Cancer
Vibecotamab (XmAb14045) is a potent bispecific antibody targeting both CD123 and CD3. Vibecotamab targets T cell-mediated killing of CD123-expressing cells, regardless of T cell antigen specificity. Vibecotamab is a full length immunoglobulin molecule. Vibecotamab can be studied in research for diseases such as Myelodysplastic syndrome and acute myeloid leukemia. Recommend Isotype Control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3 .

HY-P990045

Lixudebart ALE.F02	Claudin	Endocrinology
Lixudebart (ALE.F02) is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody. Lixudebart disrupts CLDN1 interactions with CD44 and MMP14, reduces renal macrophage infiltration, epithelial activation, and urinary albumin-to-creatinine ratio, and attenuates glomerulosclerosis. Lixudebart can be used for the research of focal segmental glomerulosclerosis .

HY-P99382

Vopratelimab JTX 2011; 37A10	Inhibitory Antibodies	Inflammation/Immunology Cancer
Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab has antitumor immune response .

HY-P990032

Belrestotug EOS-448; EOS884448; GSK4428859A	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Belrestotug (EOS-448) is an antagonistic anti-TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity. Belrestotug can be used for cancer and immunological research such as colon cancer .

HY-P990048

Muzastotug ADG126	CTLA-4	Cancer
Muzastotug is a humanized immunoglobulin G1-kappa, anti-CTLA4 monoclonal antibody. Muzastotug is an immunostimulant and antineoplastic .

HY-P99698

Lesabelimab LDP	PD-1/PD-L1	Inflammation/Immunology Cancer
Lesabelimab (LDP) is an immunoglobulin G1-kappa anti-CD274 monoclonal antibody. CD274 is an immune checkpoint ligand, represses antitumour immunity through the interaction with PDCD1 receptor .

HY-P990079

Renvistobart BMS-986207; ONO-4686	CD28	Inflammation/Immunology
Renvistobart is an immunoglobulin G1-κ, anti-[Homo sapiens TIGIT (T cell immunoreceptor with Ig domain and ITIM, VSIG9, VSTM3)] Homo sapiens monoclonal antibody .

HY-P990020

Eglatoprutug FSI-174	c-Kit	Others
Eglatoprutug is an humanized immunoglobulin *G1-kappa, anti-c-Kit* monoclonal antibody .

HY-P990039

Falbikitug	Inhibitory Antibodies	Cancer
Falbikitug is a humanized immunoglobulin G1-kappa, anti-LIF monoclonal antibody. Falbikitug is an antineoplastic .

HY-P990080

Sovipostobart BMS-986249	CTLA-4	Cancer
Sovipostobart is an immunoglobulin G1-kappa, anti-CTLA-4 human monoclonal antibody with cleavable prodomain. Sovipostobart is an immunostimulant and antineoplastic .

HY-P991135

Enzelkitug RO-7502175; RG-6411	CCR	Cancer
Enzelkitug is a humanized immunoglobulin G1-κ monoclonal antibody targeting the human C-C motif chemokine receptor 8 (CCR8). Enzelkitug is promising for research of various solid tumors and hematological malignancies .

HY-P991153

Potravitug	Virus Protease	Infection
Potravitug is a humanized immunoglobulin G1-κ monoclonal antibody targeting the major capsid protein VP1 of BK polyomavirus (BKV). Potravitug is promising for research of BKV-infection-related diseases, such as BKV-induced nephropathy after organ transplantation .

HY-P991134

Elegrobart	IGF-1R	Inflammation/Immunology
Elegrobart is an immunoglobulin G1-κ monoclonal antibody targeting the human insulin-like growth factor 1 receptor (IGF1R). Elegrobart is promising for research of diseases associated with abnormal IGF1R signaling, especially thyroid eye disease .

HY-P992099

Afivastobart AB598	NTPDase	Cancer
Afivastobart (AB598) is a human ENTPD1 (CD39)-targeting monoclonal antibody with antineoplastic activity.Afivastobart binds as a monoclonal antibody to modulate Homo sapiens ENTPD1 activity.Afivastobart constitutes a glycoform alfa immunoglobulin G1-kappa monoclonal antibody .

HY-P991139

Futermestotug	CTLA-4	Cancer
Futermestotug is a humanized immunoglobulin G1-κ monoclonal antibody targeting human cytotoxic T-lymphocyte associated protein 4 (CTLA4). Futermestotug is promising for research of various malignant tumors .

HY-P992105

Corveldebart	ANGPTL	Inflammation/Immunology
Corveldebart is a monoclonal antibody of immunoglobulin G1-kappa that targets ANGPTL4. Corveldebart can be used as an immunomodulator .

HY-P992394

JNJ-55920839 CNTO-6358	IFNAR	Inflammation/Immunology
JNJ-55920839 (CNTO-6358) is a fully human immunoglobulin G1κ monoclonal antibody and a selective Interferon α/ω neutralizer, with a K_d value of 0.9-10.7 pM against hIFNα and a K_d of 1.44 pM against IFNω. JNJ-55920839 can be used in research related to systemic lupus erythematosus .

HY-P992113

Evabosmig	β-catenin Wnt	Metabolic Disease
Evabosmig is a multispecific antibody targeting SOST, DKK-1 and ALB. Evabosmig can be used for the study of osteoporosis .

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