2749515-10-2
2749515-10-2
Chemical Structure
Lixudebart
Synonym(s): ALE.F02
- CAS No.: 2749515-10-2
- Formula:N/A
- Molecular Weight:(144.94 kDa)
SMILES: [Lixudebart]
Biological Activity: Lixudebart (ALE.F02) is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody. Lixudebart disrupts CLDN1 interactions with CD44 and MMP14, reduces renal macrophage infiltration, epithelial activation, and urinary albumin-to-creatinine ratio, and attenuates glomerulosclerosis. Lixudebart can be used for the research of focal segmental glomerulosclerosis[1].
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Lixudebart | 98.88% | Lixudebart (ALE.F02) is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody. Lixudebart disrupts CLDN1 interactions with CD44 and MMP14, reduces renal macrophage infiltration, epithelial activation, and urinary albumin-to-creatinine ratio, and attenuates glomerulosclerosis. Lixudebart can be used for the research of focal segmental glomerulosclerosis. | ||||||||||||||||||||
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References
Keywords
