2 Results for "

intestinal transit inducer

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "intestinal transit inducer" in MCE Product Catalog:

Casanthranol
Casanthranol
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Cat. No.: HY-B2134
CAS No.: 8024-48-4
Category:  

Natural Products other families Metabolic Disease Plants Disease Research Fields

Target:  

α-synuclein

Casanthranol is a naturally derived, orally active mixture of anthraquinone glycosides that exhibits inhibitory activity against α-synuclein and bioactivities related to laxation . Casanthranol inhibits seed-induced α-synuclein fibrillation in cell-free systems and rescues preformed fibril-induced cytotoxicity in differentiated N2a cells. Casanthranol promotes intestinal transit in both the small and large intestines of mice with experimental constipation. Casanthranol can be used in research related to constipation .
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Strictinin
Strictinin
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Cat. No.: HY-135319
CAS No.: 517-46-4
Purity:  97.15%
Category:  

Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Theaceae

Target:  

Bacterial Antibiotic ERK JNK NF-κB ROR Apoptosis Caspase GSK-3 Akt PI3K

Strictinin is an orally active phenolic compound. Strictinin reduces xanthine oxidase activity, uric acid production, and the activation of ERK1/2, JNK, NF-κB, and NLRP3 inflammasome components in hepatocytes treated with Xanthine (HY-W017389). Strictinin decreases elevated serum uric acid levels and enhanced xanthine oxidase activity in mice treated with potassium oxonate. Strictinin acts as a ROR1 inhibitor and exhibits anticancer activity against highly aggressive non-androgen-dependent prostate cancer. Strictinin induces cancer cell apoptosis (apoptosis), arrests cell cycle, and inhibits cancer cell migration, invasion, and epithelial-mesenchymal transition. Strictinin modulates gut microbiota, inhibits bacterial growth and biofilm formation, accelerates small intestinal transit, and blocks viral entry and replication. Strictinin can be used in research related to hyperuricemia, androgen receptor-negative non-androgen-dependent prostate cancer, triple-negative breast cancer, bacterial infections, constipation, coronavirus infections, dental caries, and infections caused by influenza A, influenza B, and human parainfluenza virus type 1 .
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