50 Results for "

leukocyte migration

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "leukocyte migration" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-P74583
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A9; 60B8AG; Prev. CAGB; CGLB; Prev. CFAG; MIF; MRP-14; NIF; MRP14; Protein S100-A9; P14; Calgranulin B; migration Inhibitory Factor-Related Protein 14; S100 Calcium-Binding Protein A9 (Calgranulin B); leukocyte L1 Complex Heavy Chain; S100 Calcium-Bin
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6
6 Cited Publications
Cat. No.: HY-15701
CAS No.: 344897-95-6
Purity:  ≥98.0%
Research Areas:  

Inflammation/Immunology

Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling .
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4
4 Cited Publications
Cat. No.: HY-110247
CAS No.: 433249-94-6
Purity:  99.67%
TRAF-STOP inhibitor 6877002 is a selective CD40-TRAF6 interaction inhibitor. TRAF-STOP inhibitor 6877002 exerts anti-atherosclerotic activity by blocking the CD40-TRAF6 signaling pathway, inhibiting classical monocyte activation, leukocyte recruitment, and macrophage activation and migration. TRAF-STOP inhibitor 6877002 reduces the phosphorylation levels of signaling intermediates in the canonical NF-κB pathway .
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4
4 Cited Publications
Cat. No.: HY-P71275
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; migration Inhibitory Factor-Related Protein 8; Calgranulin-A; leukocyte L1 Complex Light Chain; CP-10; Calprote
Species:  
Rat
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2
2 Cited Publications
Cat. No.: HY-114041
CAS No.: 552830-51-0
Purity:  95.30%
Synonyms: RvE1
Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production .
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2
2 Cited Publications
Cat. No.: HY-P70532
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A9; 60B8AG; Prev. CAGB; CGLB; Prev. CFAG; MIF; MRP-14; NIF; MRP14; Protein S100-A9; P14; Calgranulin B; migration Inhibitory Factor-Related Protein 14; S100 Calcium-Binding Protein A9 (Calgranulin B); leukocyte L1 Complex Heavy Chain; S100 Calcium-Bin
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1
1 Cited Publications
Cat. No.: HY-P2294A
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

pm26TGF-β1 TFA peptide is a peptide that mimics a portion of the human TGF-β1 molecule. pm26TGF-β1 peptide TFA shows high affinity for the TGF-β1 receptor. pm26TGF-β1 peptide TFA displays potent anti-inflammatory properties and does not exhibit neutrophils’ chemoattraction .
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1
1 Cited Publications
Cat. No.: HY-P73671
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; migration Inhibitory Factor-Related Protein 8; Calgranulin-A; leukocyte L1 Complex Light Chain; CP-10; Calprote
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1
1 Cited Publications
Cat. No.: HY-P71076
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; migration Inhibitory Factor-Related Protein 8; Calgranulin-A; leukocyte L1 Complex Light Chain; CP-10; Calprote
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Cat. No.: HY-N3945
CAS No.: 475-81-0
Synonyms: O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396
Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 (PDE4), with a Ki of 3.4 µM in human bronchial tissues and polymorphonuclear leukocytes. Glaucine induces relaxation of human isolated bronchi by antagonizing calcium channels. Additionally, Glaucine inhibits the activation of NF-κB, leading to a reduction in the expression of the MMP-9 gene, thereby suppressing the migration and invasion of breast cancer cells. Therefore, Glaucine holds potential for research in asthma and breast cancer .
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Cat. No.: HY-132828
CAS No.: 1639303-73-3
Synonyms: LT3001; DHDMIQK(KAP)
Odatroltide (LT3001; DHDMIQK(KAP)) is a P-selectin inhibitor. Odatroltide is a peptide molecule comprising a tripeptide Pro-Ala-Lys (PAK) and an (S)-6,7-dihydroxy-1,1-dimethyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid domain. Odatroltide can restore cerebral blood flow, scavenge free radicals, and inhibit leukocyte migration. Odatroltide possesses thrombolytic and anti-thrombotic activities .
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Cat. No.: HY-19151
CAS No.: 141283-87-6
Synonyms: IS-741
Target:  

Integrin Phospholipase

Research Areas:  

Inflammation/Immunology

Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .
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Cat. No.: HY-145728B
Purity:  97.08%
Synonyms: (R/S)-ISIS-2302
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

(R/S)-Alicaforsen is the racemate of Alicaforsen composed of R and S configurations. Alicaforsen is a 20-base antisense oligonucleotide inhibiting ICAM-1 production, which is an important adhesion molecule involved in leukocyte migration and trafficking to the site of inflammation.
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Cat. No.: HY-121852
CAS No.: 447459-51-0
Purity:  98.85%
Synonyms: SCH-225336
Target:  

Cannabinoid Receptor

Research Areas:  

Inflammation/Immunology

SCH 336 is a potent, selective, inverse and orally active CB2 agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice .
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Cat. No.: HY-19151A
CAS No.: 141284-73-3
Synonyms: IS-741 sodium
Target:  

Integrin Phospholipase

Research Areas:  

Inflammation/Immunology

Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .
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Cat. No.: HY-114041S
Synonyms: RvE1-d4
Resolvin E1-d4 (RvE1-d4) is deuterium labeled Resolvin E1. Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production .
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Cat. No.: HY-E70303
CAS No.: 2178088-82-7
Synonyms: FUT6
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Fucosyltransferase 6 is a fucosyltransferase that mediates the expression of the tetrasaccharide Sialyl-Lewis x (sLex, CD15s) on the surface of leukocytes. sLex participates in E-selectin-mediated leukocyte rolling and is related to the migration of leukocytes out of blood vessels .
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Cat. No.: HY-114041S1
CAS No.: 2714040-94-3
Synonyms: RvE1-d4-1
Resolvin E1-d4-1 is the deuterium labeled Resolvin E1. Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production .
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Cat. No.: HY-P2294
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology

pm26TGF-β1 peptide is a peptide that mimics a portion of the human TGF-β1 molecule. pm26TGF-β1 peptide shows high affinity for the TGF-β1 receptor. pm26TGF-β1 peptide displays potent anti-inflammatory properties and does not exhibit neutrophils’ chemoattraction .
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Cat. No.: HY-19151B
CAS No.: 141284-74-4
Synonyms: IS-741 potassium
Target:  

Integrin Phospholipase

Research Areas:  

Inflammation/Immunology

Fuzapladib (IS-741) potassium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib potassium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib potassium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site .
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