141284-74-4
141284-74-4
Chemical Structure
Fuzapladib potassium
Synonym(s): IS-741 potassium
- CAS No.: 141284-74-4
- Formula:C15H20F3KN3O3S
- Molecular Weight:418.50
InChIKey: FOCFRHIBKVZLMG-UHFFFAOYSA-N
SMILES: O=C(C1CCCCC1)NC2=CC(C(F)(F)F)=CN=C2NS(=O)(CC)=O.[K]
Biological Activity: Fuzapladib (IS-741) potassium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib potassium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib potassium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site[1][2].
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Fuzapladib potassium | Fuzapladib (IS-741) potassium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib potassium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib potassium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site. | |||||||||||||||||||||
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References
Keywords
