pm26TGF-β1 peptide
Based on 1 publication(s) in Google Scholar
pm26TGF-β1 peptide is a peptide that mimics a portion of the human TGF-β1 molecule. pm26TGF-β1 peptide shows high affinity for the TGF-β1 receptor. pm26TGF-β1 peptide displays potent anti-inflammatory properties and does not exhibit neutrophils’ chemoattraction.
For research use only. We do not sell to patients.
- Formula: C54H93N19O20S2
- Molecular Weight:1392.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) pm26TGF-β1 peptide
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Biological Activity
The synthetic pm26TGF-β1 peptide (1 μM, 10 μM and 100 μM; 24-48 hours) tested in peripheral blood mononuclear cells (PBMC) significantly down-modulates TNF-α and up-regulates IL-10 responses in an inflammatory microenvironment, leading to regulatory T cells (Treg) phenotype differentiation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male C57BL/6 mice (5-7-weeks old; 20-30g) injected with carrageenan[1]
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Dosage:100 µg/kg, 300 µg/kg or 1000 µg/kg
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Administration:Subcutaneous injection; once
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Result:Decreased neutrophils migration during inflammatory process in C57BL/6 mice.
Chemical Information
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Molecular Weight 1392.56
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Formula C54H93N19O20S2
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Sequence
Ala-Cys-Glu-Ser-Pro-Leu-Lys-Arg-Gln-Cys-Gly-Gly-Gly-Ser
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Sequence Shortening
ACESPLKRQCGGGS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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