141284-73-3

Fuzapladib sodium Chemical Structure
141284-73-3

Chemical Structure

Fuzapladib sodium

Synonym(s): IS-741 sodium

  • CAS No.: 141284-73-3
  • Formula:C15H20F3N3NaO3S
  • Molecular Weight:402.39

IUPAC Name: N-(2-(ethylsulfonamido)-5-(trifluoromethyl)pyridin-3-yl)cyclohexanecarboxamide, sodium salt

InChIKey: NRRNIBATADCYRE-UHFFFAOYSA-N

SMILES: O=C(C1CCCCC1)NC2=CC(C(F)(F)F)=CN=C2NS(=O)(CC)=O.[Na]

Biological Activity: Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site[1][2].

Cat. No. Product Name Purity Description Pricing
HY-19151A
Fuzapladib sodium 99.61% Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site.
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