Search Result

Results for "

mustard

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldose Reductase (1) Apoptosis (4) Bacterial (1) Bcl-2 Family (2) Carboxypeptidase (1) Caspase (3) DNA Alkylator/Crosslinker (23) DNA/RNA Synthesis (3) Drug Derivative (4) Drug Metabolite (5) Endogenous Metabolite (5) Environmental Pollutants (1) Fluorescent Dye (1) Herbicide (3) Histone Acetyltransferase (1) HPPD (1) Isotope-Labeled Compounds (5) mAChR (1) Mitochondrial Metabolism (1) PARP (1) Protoporphyrinogen IX oxidase (1) Reactive Oxygen Species (ROS) (2) Reference Standards (8)
By Research Areas:	Cancer (30) Cardiovascular Disease (2) Infection (4) Inflammation/Immunology (1) Metabolic Disease (5) Neurological Disease (2)

By Targets:

Aldose Reductase (1)

Apoptosis (4)

Bacterial (1)

Bcl-2 Family (2)

Carboxypeptidase (1)

Caspase (3)

DNA Alkylator/Crosslinker (23)

DNA/RNA Synthesis (3)

Drug Derivative (4)

Drug Metabolite (5)

Endogenous Metabolite (5)

Environmental Pollutants (1)

Fluorescent Dye (1)

Herbicide (3)

Histone Acetyltransferase (1)

HPPD (1)

Isotope-Labeled Compounds (5)

mAChR (1)

Mitochondrial Metabolism (1)

PARP (1)

Protoporphyrinogen IX oxidase (1)

Reactive Oxygen Species (ROS) (2)

Reference Standards (8)

By Research Areas:

Cancer (30)

Cardiovascular Disease (2)

Infection (4)

Inflammation/Immunology (1)

Metabolic Disease (5)

Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17420

Cyclophosphamide Maximum Cited Publications 69 Publications Verification	DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.

HY-17420A

Cyclophosphamide hydrate Maximum Cited Publications 69 Publications Verification Cyclophosphamide monohydrate	DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

HY-137316A

*Phosphoramide mustard* cyclohexanamine** 5+ Cited Publications	DNA Alkylator/Crosslinker Drug Metabolite	Cancer
Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage .

HY-14798

Palifosfamide 2 Publications Verification Isophosphoramide mustard; IPM; ZIO-201	DNA Alkylator/Crosslinker Drug Metabolite	Cancer
Palifosfamide is a novel DNA alkylator and the active metabolite of ifosfamide, with antitumor activity.

HY-113063

3-Methyl-2-oxovaleric acid 3 Publications Verification	Endogenous Metabolite	Metabolic Disease
3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone .

HY-13593

Chlorambucil 4 Publications Verification CB-1348; WR-139013	DNA Alkylator/Crosslinker	Neurological Disease Cancer
Chlorambucil (CB-1348), an orally active antineoplastic agent, is a CNS-penetrant bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .

HY-137316

Phosphoramide mustard	DNA Alkylator/Crosslinker Drug Metabolite	Cancer
Phosphoramide mustard is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard induces DNA damage .

HY-W017386

3-Methyl-2-oxovaleric acid sodium 3 Publications Verification	Endogenous Metabolite	Metabolic Disease
3-Methyl-2-oxovaleric acid sodium is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid sodium is a biomarker of mustard airway diseases (MADs) and uric acid stone .

HY-137910

Tembotrione	Environmental Pollutants HPPD Herbicide	Infection
Tembotrione is a herbicide belonging to the HPPD (dioxygenase) inhibitor class with crop selectivity. Tembotrione effectively controls a variety of weeds including broadleaf and gramineous species by disrupting carotenoid synthesis, which leads to chlorophyll degradation and leaf whitening. Mixing Tembotrione with isoxaflutole or adding surfactants optimizes its efficacy and reduces phytotoxicity, with no residual impact on subsequent cruciferous crops, thus helping to increase maize grain yield. The activity of Tembotrione decreases under drought conditions, and under specific conditions (such as double-dose treatment), it may cause reversible yellowing and even yield reduction in crops such as poppy .

HY-16405

PR-104	DNA Alkylator/Crosslinker	Cancer
PR-104 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A .

HY-17420S

Cyclophosphamide-d4	DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide-d₄ is the deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant .

HY-113063R

3-Methyl-2-oxovaleric acid (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
3-Methyl-2-oxovaleric acid (Standard) is the analytical standard of 3-Methyl-2-oxovaleric acid (HY-113063). This product is intended for research and analytical applications. 3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone.

HY-W127705

*Quinacrine mustard* dihydrochloride** 1 Publications Verification	Fluorescent Dye	Others
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes .

HY-70003

Carboxypeptidase G2 (CPG2) Inhibitor CPG2 Inhibitor	Carboxypeptidase	Cancer
Carboxypeptidase G2 (CPG2) Inhibitor is a novel CPG2 inhibitor with an K_i of 0.3 μM. Carboxypeptidase G2 (CPG2) Inhibitor effectively neutralizes the CPG2 activity in non-tumor sites, allowing for earlier administration of the drug and forming a complementary strategy with antibody clearance strategies. Carboxypeptidase G2 (CPG2) Inhibitor can be used for the study of antibody-directed enzyme prodrug therapy (ADEPT) .

HY-172314

ACHM-025	Aldose Reductase Drug Derivative	Cancer
ACHM-025 is a prodrug, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent. ACHM-025 can be used for the research of cancer, such as leukemia .

HY-17420AR

Cyclophosphamide hydrate (Standard) Cyclophosphamide monohydrate (Standard)	Reference Standards DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide (hydrate) (Standard) is the analytical standard of Cyclophosphamide (hydrate). This product is intended for research and analytical applications. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.

HY-W199190

2-CEES	DNA/RNA Synthesis	Cancer
2-CEES is a mustard gas analog forms only DNA monoadducts. 2-CEES induces centrosome amplification in human and mouse cells. 2-CEES induces centrosome amplification and chromosome instability .

HY-W275553

4-Decanol	DNA Alkylator/Crosslinker	Infection
4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of Aflatoxin B1 (HY-N6615) and MNNG (HY-128612) in Salmonella typhimurium TA100 .

HY-16232

Glufosfamide D 19575; Glucosylifosfamide mustard	Apoptosis Caspase Bcl-2 Family	Cancer
Glufosfamide is a glucose-conjugated alkylating cytotoxic agent and a derivative of Ifosfamide (HY-17419). Glufosfamide induces apoptosis frequency and increase the expression of caspase-9 and caspase-3 in cancer cells. Glufosfamide shows great anti-tumor activity in MiaPaCa-2-RFP mouse model. Glufosfamide can be used for the study of hepatocellular carcinoma, prostate cancer and pancreatic carcinoma .

HY-114577

Palifosfamide tromethamine 2 Publications Verification Isophosphoramide mustard tromethamine; IPM tromethamine; ZIO-201 tromethamine	DNA Alkylator/Crosslinker	Cancer
Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.

HY-W017386S

3-Methyl-2-oxovaleric acid-d8 sodium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
3-Methyl-2-oxovaleric acid-d₈ sodium is the deuterium labeled 3-Methyl-2-oxovaleric acid. 3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone .

HY-124892A

*Acetylethylcholine mustard* hydrochloride** Acetyl-AF64	Histone Acetyltransferase	Neurological Disease
Acetylethylcholine mustard hydrochloride (Acetyl-AF64) is an inhibitor of choline acetyl-transferase that reduces the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC₅₀) of 1.22 mM. Acetylethylcholine mustard hydrochloride is an irreversible ligand for the high affinity choline transport system. Acetylethylcholine mustard hydrochloride is also a cholinotoxin. Acetylethylcholine mustard hydrochloride is a precursor for ethylcholine mustard aziridinium ion .

HY-136327

Phenylacetic acid mustard	DNA Alkylator/Crosslinker	Cancer
Phenylacetic acid mustard is the major metabolite of the cancer chemotherapeutic agent Chlorambucil (HY-13593). Chlorambucil is an alkylating agent with antitumor activity .

HY-121713

Aniline mustard N,N-Bis(2-chloroethyl)aniline	Apoptosis Mitochondrial Metabolism Caspase DNA/RNA Synthesis PARP Reactive Oxygen Species (ROS)	Cancer
Aniline mustard (N, n-BIS (2-chloroethyl) aniline) is an anticancer agent .

HY-116948

Azo-mustard	Drug Derivative	Cancer
Azo-mustard is a nitrogen mustard derivative with mutagenic effects in Drosophila melanogaster males .

HY-137316AR

*Phosphoramide mustard* cyclohexanamine (Standard)**	Reference Standards DNA Alkylator/Crosslinker Drug Metabolite	Cancer
Phosphoramide mustard (cyclohexanamine) (Standard) is the analytical standard of Phosphoramide mustard (cyclohexanamine). This product is intended for research and analytical applications. Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage[1][2].

HY-17420S1

Cyclophosphamide-d8	Isotope-Labeled Compounds DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide-d₈ is deuterium labeled Cyclophosphamide. Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.

HY-W010778

N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine	Drug Derivative	Others
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-quinazolin-4-amine is a quinazoline derivative that has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.

HY-179054

Apoptosis inducer 51	Apoptosis Reactive Oxygen Species (ROS) DNA/RNA Synthesis	Cancer
Apoptosis inducer 51 (Compound 5d) is an apoptosis inducer. Apoptosis inducer 51 exhibits strong inhibitory activity against MDA-MB-231 cells. Apoptosis inducer 51 inhibits cell invasion and migration, induces G2/M phase cell cycle arrest and cell apoptosis. Apoptosis inducer 51 causes DNA damage, ROS burst and mitochondrial membrane potential (MMP) collapse. Apoptosis inducer 51 can be used for the study of triple-negative breast cancer.

HY-16406

PR-104 sodium	DNA Alkylator/Crosslinker	Cancer
PR-104 (sodium) is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104 (sodium), as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A .

HY-105815

Chlornaphazine	DNA Alkylator/Crosslinker	Cancer
Chlornaphazine, a nitrogen mustard derivative, is a bifunctional alkylating agent. Chlornaphazine is an antineoplastic agent, which can be used for the study of polycythemia vera and Hodgkin’s disease .

HY-163570

PPO-IN-11	Protoporphyrinogen IX oxidase	Others
PPO-IN-11 (Compound 10bh) is an inhibitor for protoporphyrinogen IX oxidase (PPO), that inhibits nicotiana tabacum PPO (NtPPO) with K_i of 0.0603 μM. PPO-IN-11 exhibits herbicidal activities against dicot weeds Leaf mustard, Chickweed, Chenopodium serotinum and monocot weeds Alopecurus aequalis, Poa annua, and Polypogon fugax with a dose of 150 g a.i./ha .

HY-N12974

Glucoconringiin	Others	Others
Glucoconringiin is a mustard oil glucoside that can be isolated from Cruciferae and Tropaeolaceae. Glucoconringiin acts as a feeding stimulant for the larvae of Plutella maculipennis .

HY-17420AS

Cyclophosphamide-d8 hydrate Cyclophosphamide-d8 monohydrate	Isotope-Labeled Compounds DNA Alkylator/Crosslinker	Cancer
Cyclophosphamide-d₈ (hydrate) is the deuterium labeled Cyclophosphamide hydrate. Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities .

HY-119899

BO-0742	Drug Derivative	Cancer
BO-0742, a derivative of AHMA and N-mustard, is a potent anti-cancer agent. BO-0742 significantly suppresses the growth of xenografts of human breast and ovarian cancers in mice .

HY-14798R

Palifosfamide (Standard) Isophosphoramide mustard (Standard); IPM (Standard); ZIO-201 (Standard)	Reference Standards DNA Alkylator/Crosslinker Drug Metabolite	Cancer
Benzimidazole (Standard) is the analytical standard of Benzimidazole. This product is intended for research and analytical applications. Benzimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-13593S

Chlorambucil-d8 CB-1348-d₈; WR-139013-d₈	Isotope-Labeled Compounds DNA Alkylator/Crosslinker	Cancer
Chlorambucil-d₈ is the deuterium labeled Chlorambucil. Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .

HY-13593S1

Chlorambucil-d8-1 CB-1348-d₈-1; WR-139013-d₈-1	Isotope-Labeled Compounds DNA Alkylator/Crosslinker	Cancer
Chlorambucil-d₈-1 is the deuterium labeled Chlorambucil. Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .

HY-W714171

Propoxycarbazone sodium BAY MKH 6561	Herbicide	Others
Propoxycarbazone sodium (BAY MKH 6561) is a herbicide. Propoxycarbazone sodium controls shepherd’s purse (Capsella bursa-pastoris L. Medicus), tumble mustard (Sisymbrium altissimum L.), field pennycress (Thlaspi arvense L.), and several Bromus species. Propoxycarbazone sodium also inhibits the growth of jointed goatgrass, wild oat (Avena fatua L.), and quackgrass (Elytrigia repens L. Nevski) .

HY-13593R

Chlorambucil (Standard) CB-1348 (Standard); WR-139013 (Standard)	Reference Standards DNA Alkylator/Crosslinker	Cancer
Chlorambucil (Standard) is the analytical standard of Chlorambucil. This product is intended for research and analytical applications. Chlorambucil (CB-1348), an orally active antineoplastic agent, is a bifunctional alkylating agent belonging to the nitrogen mustard group. Chlorambucil can be used for the research of lymphocytic leukemia, ovarian and breast carcinomas, and Hodgkin’s disease .

HY-W714171R

Propoxycarbazone sodium (Standard) BAY MKH 6561 (Standard)	Herbicide Reference Standards	Others
Propoxycarbazone (sodium) (Standard) is the analytical standard of Propoxycarbazone (sodium). This product is intended for research and analytical applications. Propoxycarbazone sodium (BAY MKH 6561) is a herbicide. Propoxycarbazone sodium controls shepherd’s purse (Capsella bursa-pastoris L. Medicus), tumble mustard (Sisymbrium altissimum L.), field pennycress (Thlaspi arvense L.), and several Bromus species. Propoxycarbazone sodium also inhibits the growth of jointed goatgrass, wild oat (Avena fatua L.), and quackgrass (Elytrigia repens L. Nevski) .

HY-127138

Arctigenin mustard	Others	Others
Arctigenin mustard is an active compound.

HY-186083

Propylbenzilylcholine mustard	mAChR	Cardiovascular Disease
Propylbenzilylcholine mustard (PrBCM) is an irreversible, covalently binding selective antagonist targeting rat cardiac muscarinic receptors, with a preference for muscarinic receptor subtypes that show low affinity for agonists. Propylbenzilylcholine mustard inactivates such receptors in a dose- and time-dependent manner in vitro, and its receptor selectivity remains stable across different ionic strengths and in GTP-containing buffer systems. Propylbenzilylcholine mustard can be applied to basic pharmacological studies on the structure and function of muscarinic receptors, especially focusing on the heterogeneity of cardiac muscarinic receptors and related cardiovascular pharmacological research .

HY-N18810

Mustard oil	Bacterial	Cardiovascular Disease Infection Inflammation/Immunology
Mustard oil has antibacterial and anti-inflammatory properties and can be used in research on skin diseases, lung diseases, arthritis, and cardiovascular complications.

HY-P2872A

*Thioglucosidase, Sinapis alba (white mustard) seed*	Endogenous Metabolite	Metabolic Disease
Thioglucosidase, Sinapis alba (white mustard) seed (EC 3.2.1.147) hydrolyzes the S-glucosidic bond of a glucosinolate substrate to form an unstable aglycone that rearranges with the loss of sulfate primarily to the isothiocyanate, though thiocyanates and nitriles are also formed.

HY-16232R

Glufosfamide (Standard) D 19575 (Standard); Glucosylifosfamide mustard (Standard)	Reference Standards Apoptosis Bcl-2 Family Caspase	Cancer
Glufosfamide (Standard) is the analytical standard of Glufosfamide. This product is intended for research and analytical applications. Glufosfamide is a glucose-conjugated alkylating cytotoxic agent and a derivative of Ifosfamide (HY-17419). Glufosfamide induces apoptosis frequency and increase the expression of caspase-9 and caspase-3 in cancer cells. Glufosfamide shows great anti-tumor activity in MiaPaCa-2-RFP mouse model. Glufosfamide can be used for the study of hepatocellular carcinoma, prostate cancer and pancreatic carcinoma .

HY-W275553R

4-Decanol (Standard)	DNA Alkylator/Crosslinker Reference Standards	Infection
4-Decanol (Standard) is the analytical standard of 4-Decanol (HY-W275553). This product is intended for research and analytical applications. 4-Decanol is an antimutagenic compound, that can be isolated from mustard leaves. 4-Decanol inhibits mutagenic activities of Aflatoxin B1 (HY-N6615) and MNNG (HY-128612) in Salmonella typhimurium TA100 .

HY-182682

IOB-82 NSC-146171	DNA Alkylator/Crosslinker	Cancer
IOB-82 is a bifunctional alkylating agent. IOB‑82 induces marked nuclear and cytoplasmic alterations, elicits severe chromatid and chromosome aberrations, and remodels chromosome ploidy. IOB-82 exerts dose-dependent radiomimetic effects and preferentially cytotoxic to large A-type rat ascites cells. IOB-82 can be applied in the research of melanoma‑derived tumors and leukemia .

Cat. No.	Product Name	Type