29424-96-2

4',​7-​Di-​O-​methylnaringenin Chemical Structure
29424-96-2

Chemical Structure

4',​7-​Di-​O-​methylnaringenin

Synonym(s): (-)-Naringenin 4',​7-dimethyl Ether; (-)-NRG-DM

  • CAS No.: 29424-96-2
  • Formula:C17H16O5
  • Molecular Weight:300.31

IUPAC Name: (S)-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)chroman-4-one

InChIKey: CKEXCBVNKRHAMX-HNNXBMFYSA-N

SMILES: O=C1C[C@@H](C2=CC=C(OC)C=C2)OC3=CC(OC)=CC(O)=C13

Biological Activity: 4',​7-​Di-​O-​methylnaringenin ((−)-NRG-DM) is a flavonoid found in Renealmia alpinia[1]. (−)-NRG-DM inhibits Nav1.7, Nav1.8 and Kv2.1 channels and has analgesic activity. Intraperitoneal administration of (−)-NRG-DM dose-dependently attenuated pain in a formalin-induced mouse inflammatory pain model and mustard oil-induced mouse colorectal pain model[2].

Cat. No. Product Name Purity Description Pricing
HY-N1884
4',​7-​Di-​O-​methylnaringenin 99.20% 4',​7-​Di-​O-​methylnaringenin ((−)-NRG-DM) is a flavonoid found in Renealmia alpinia. (−)-NRG-DM inhibits Nav1.7, Nav1.8 and Kv2.1 channels and has analgesic activity. Intraperitoneal administration of (−)-NRG-DM dose-dependently attenuated pain in a formalin-induced mouse inflammatory pain model and mustard oil-induced mouse colorectal pain model[2].
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