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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
nuclear extract
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "nuclear extract" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N2481
CAS No.: 36948-76-2
Synonyms: Oroxyloside; Oroxylin A-7-O-β-D-glucuronide
1
1 Cited Publications
Cat. No.: HY-N0167
CAS No.: 80321-63-7
Synonyms: Ginsenoside C-Mx1; Gypenoside IX
Category:
Triterpenes Terpenoids Cucurbitaceae Plants Endogenous metabolite Disease Research Fields Gynostemma pentaphyllum (Thunb.) Makino Cancer
Target:
Cat. No.: HY-W011548
CAS No.: 2096-10-8
Target:
Domaines de recherche:
2-Aminoadenosine is a modified adenine base and adenosine analog that stabilizes RNA duplexes and enhances template-directed nucleotide condensation reactions. 2-Aminoadenosine forms three hydrogen bonds with uracil to increase the melting temperature of hybrid strands, thereby stabilizing uracil-containing RNA duplexes .
Cat. No.: HY-19772
CAS No.: 1018673-42-1
Synonyms: ESM-HDAC391; CHR-5154; HDAC-IN-3
Domaines de recherche:
GSK3117391 (ESM-HDAC391; CHR-5154; HDAC-IN-3) is an orally active HDAC inhibitor with a IC50 of 55 nM. Using esterase-sensitive motif technology, GSK3117391 is selectively converted into its active acid metabolite HDAC189 in cells expressing carboxylesterase-1. GSK3117391 induces sustained global protein acetylation in monocytes, inhibits the production of proinflammatory cytokines, depletes circulating monocytes, downregulates the expression of CSF1R, and inhibits monocyte adhesion and differentiation. GSK3117391 can be used in the research of chronic inflammatory diseases .
Cat. No.: HY-N0475
CAS No.: 74285-86-2
Synonyms: Hypolide; (+)-Triptophenolide
Cat. No.: HY-136951
CAS No.: 347397-83-5
Target:
Domaines de recherche:
cp028 is a potent pre-mRNA splicing inhibitor. cp028 inhibits splicing in HeLa nuclear extract with an IC50 value of 54 µM .
Cat. No.: HY-P5156
CAS No.: 207621-38-3
Target:
Domaines de recherche:
Cat. No.: HY-W016455
CAS No.: 4286-55-9
Target:
Domaines de recherche:
6-Bromo-1-hexanol is a chemical intermediate. 6-Bromo-1-hexanol can be used to synthesize HDAC inhibitor intermediates and bromoalkyl glycosides via Fischer glycosylation in microreactors .
Cat. No.: HY-N10133
CAS No.: 119240-82-3
Synonyms: 3′-Prenylnaringenin
Cat. No.: HY-U00429
CAS No.: 1015231-98-7
Target:
Domaines de recherche:
NOT Receptor Modulator 1 is a nuclear receptor Nurr-1/NOT modulator extracted from patent WO 2008034974 A1, Example 39 in table1.
Cat. No.: HY-N2481R
CAS No.: 36948-76-2
Synonyms: Oroxyloside (Standard); Oroxylin A-7-O-β-D-glucuronide (Standard)
Cat. No.: HY-P10825
Target:
Domaines de recherche:
Cat. No.: HY-151263
CAS No.: 3031784-60-5
Target:
Domaines de recherche:
G4/HDAC-IN-1 (compound a6) is a G4/HDAC dual-targeting compound. G4/HDAC-IN-1 inhibits intracellular HDAC activity with an IC50 value of 1.1 μM, and induces G4 formation. G4/HDAC-IN-1 inhibits TNBC proliferation and tumor growth in TNBC xenograft model. G4/HDAC-IN-1 can be used for the research of cancer .
Cat. No.: HY-N11507
CAS No.: 2319668-87-4
Synonyms: TKV
Target:
Cat. No.: HY-N0475R
CAS No.: 74285-86-2
Synonyms: Hypolide (Standard); (+)-Triptophenolide (Standard)
Cat. No.: HY-185554
CAS No.: 626200-64-4
Target:
Domaines de recherche:
HDAC-IN-102 (Compound 21) is a histone deacetylase (HDAC) inhibitor with an IC50 of 58 μM. HDAC-IN-102 inhibits total HDAC activity and exhibits partial subtype selectivity, with the R-isomer targeting HDAC2 and the S-isomer targeting HDAC8. HDAC-IN-102 exerts antioxidant effects by scavenging DPPH free radicals. HDAC-IN-102 can be used in cancer-related research .
Cat. No.: HY-P2044
CAS No.: 585535-37-1
Category:
Target:
Cat. No.: HY-W787758
CAS No.: 24102-11-2
Synonyms: 4-yn-VPA
Target:
Domaines de recherche:
2-Propylpent-4-ynoic acid (4-yn-VPA) is a HDAC inhibitor (with an IC50 of 0.5 mM against human HDAC). 2-Propylpent-4-ynoic acid also induces P-glycoprotein function, and exhibits teratogenicity, fetal growth inhibition and neurotoxicity. 2-Propylpent-4-ynoic acid shows significant stereospecific teratogenic effects, with the S-enantiomer being more teratogenic than the R-enantiomer and other analogs. The neurotoxicity of 2-Propylpent-4-ynoic acid is independent of its stereochemical structure. 2-Propylpent-4-ynoic acid has been used in studies related to the pathogenesis of colon cancer and neural tube defects such as exencephaly .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
