207621-38-3
Chemical Structure
BDS-I
- CAS No.: 207621-38-3
- Formula:C210H297N57O56S6
- Molecular Weight:4708.34
SMILES: O=C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CSSC[C@@H]2NC3=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCCCN)C(N[C@@H](CC6=CNC7=CC=CC=C67)C(N8[C@@H](CCC8)C(N[C@@H](CC(N)=O)C(N[C@H]3[C@@H](C)CC)=O)=O)=O)=O)=O)=O)NC9=O)C(N[C@@H](CO)C(NCC(N[C@@H](CCCCN)C(N%10[C@@H](CCC%10)C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC%11=CNC%12=CC=CC=C%11%12)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC%13=CC=C(C=C%13)O)C(N%14[C@@H](CCC%14)C(N[C@@H](CC%15=CNC=N%15)C(O)=O)=O)=O)=O)NC2=O)C(N%16[C@@H](CCC%16)C(NCC(NCC(N[C@@H](CC%17=CC=C(C=C%17)O)C(NCC(N[C@@H](CC%18=CC=C(C=C%18)O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@H]9CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
Biological Activity: BDS-I known as blood depressing substance, is a marine toxin which can be extracted from Anemonia sulcata. BDS-I is a specific inhibitor of Potassium Channel, targeting to Kv3.4. BDS-I inhibits Aβ1-42-induced enhancement of KV3.4 activity, caspase-3 activation, and abnormal nuclear morphology of NGF-differentiated PC-12 cells. BDS-I reverts the Aβ peptide-induced cell death[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BDS-I | BDS-I known as blood depressing substance, is a marine toxin which can be extracted from Anemonia sulcata. BDS-I is a specific inhibitor of Potassium Channel, targeting to Kv3.4. BDS-I inhibits Aβ1-42-induced enhancement of KV3.4 activity, caspase-3 activation, and abnormal nuclear morphology of NGF-differentiated PC-12 cells. BDS-I reverts the Aβ peptide-induced cell death. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
