2 Results for "

ocular hypertension diseases

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ocular hypertension diseases" in MCE Product Catalog:

Cat. No.: HY-P10019
CAS No.: 2243292-26-2
Synonyms: NLY01
Target:  

GCGR

Pegsebrenatide (NLY01) is a blood-brain barrier-penetrant GLP-1R agonist. Pegsebrenatide alleviates retinal inflammation and neuronal death secondary to ocular hypertension . Pegsebrenatide significantly delays onset and reduces disease severity in experimental autoimmune encephalomyelitis . Pegsebrenatide inhibits the formation of A1 reactive astrocytes in nerve cells and reduces the loss of retinal ganglion cells and dopaminergic neurons. Pegsebrenatide exerts neuroprotective effects in a mouse model of Parkinson's disease by directly preventing microglia-mediated conversion of astrocytes to the A1 neurotoxic phenotype. Pegsebrenatide can be used for research on glaucoma, Parkinson's disease, and multiple sclerosis .
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Cat. No.: HY-B1035C
CAS No.: 27867-05-6
Synonyms: (R)-Bunolol hydrochloride
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

ent-Levobunolol ((R)-Bunolol) hydrochloride is a competitive β-adrenergic receptor blocker. ent-Levobunolol hydrochloride inhibits the transmission of sympathetic nerve impulses, reduces the production of aqueous humor, and constricts blood vessels in the eye, thereby reducing intraocular pressure. ent-Levobunolol hydrochloride is promising for research of ocular hypertension diseases such as glaucoma .
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